When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Systemic candidiasis

ბოლო მიმოხილვა: 10 Jun 2025
ბოლო განახლება: 23 Mar 2023

შეჯამება

განსაზღვრება

ანამნეზი და გასინჯვა

ძირითადი დიაგნოსტიკური ფაქტორები

  • fever
სრული ტექსტი

სხვა დიაგნოსტიკური ფაქტორები

  • tachycardia
  • tachypnea
  • hypotension
  • poor capillary refill
  • acute mental confusion
  • decreased urine output
  • low oxygen saturation
  • rash
  • hepatosplenomegaly
  • hypothermia
სრული ტექსტი

რისკფაქტორები

  • use of central venous catheter
  • exposure to broad-spectrum antibiotics
  • hemodialysis
  • surgery
  • parenteral nutrition
  • immunosuppressants (e.g., chemotherapy, systemic corticosteroids, biologic and other immunosuppressants)
  • colonization at multiple sites
  • intravenous drug use
სრული ტექსტი

დიაგნოსტიკური კვლევები

1-ად შესაკვეთი გამოკვლევები

  • blood culture
  • CBC
  • ABG
  • lactate levels
  • coagulation studies
  • renal function tests
  • liver function test
  • serum glucose
სრული ტექსტი

გასათვალისწინებელი კვლევები

  • 1,3-beta-D-glucan
  • T2 magnetic resonance assay
  • tissue biopsy
სრული ტექსტი

ახალი ტესტები

  • polymerase chain reaction
  • matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry

მკურნალობის ალგორითმი

საწყისი

suspected diagnosis

მწვავე

confirmed diagnosis: non-neutropenic patients (no complications)

confirmed diagnosis: neutropenic patients (no complications)

confirmed diagnosis: with complications

კონტრიბუტორები

ავტორები

Brenda L. Tesini, MD

Assistant Professor

Infectious Diseases

Departments of Medicine and Pediatrics

University of Rochester Medical Center

Rochester

NY

გაფრთხილება:

BLT has received honoraria from Merck for educational contributions unrelated to this topic.

მადლიერება

Dr Brenda L. Tesini would like to gratefully acknowledge Dr Jack D. Sobel and Dr Sanjay G. Revankar, previous contributors to this topic.

გაფრთხილება:

JDS declares that he has no competing interests. SR has received grants for research from Astellas, Gilead, and Merck, and has been involved in clinical trials for Cidara and Astellas.

რეცენზენტები

John Fisher, MD

Professor of Medicine

Department of Medicine

Medical College of Georgia

Augusta

GA

გაფრთხილება:

JF is an author of a number of references cited in this topic. JF is a member of the speaker's bureau for the following companies: Pfizer, Merck, and Astellas.

Jean-Michel Livrozet, MD

Praticien hospitalier

Service de medecine de la Transplantation et d'Immunologie clinique

Hopital Edouard Herriot

Lyon

France

利益声明

JML has been invited by Astellas, the manufacturer of micafungin, to attend a symposium, and invited by Gilead Sciences, manufacturer of liposomal amphotericin B, to attend different HIV conferences, and has been paid by Gilead Sciences for running HIV educational programs.

Matthew Falagas, MD, MSc, DSc

Director

Alfa Institute of Biomedical Sciences

Marousi

Athens

Greece

利益声明

MF declares that he has no competing interests.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Tsay SV, Mu Y, Williams S, et al. Burden of candidemia in the United States, 2017. Clin Infect Dis. 2020 Dec 3;71(9):e449-53.全文  摘要

Centers for Disease Control and Prevention. ​Candida auris: information for laboratorians and health professionals. Jul 2021 [internet publication].全文

Pappas PG, Kauffman CA, Andes DR, et al. Clinical practice guideline for the management of candidiasis: 2016 update by the Infectious Diseases Society of America. Clin Infect Dis. 2016 Feb 15;62(4):e1-50.全文  摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

内容使用需遵循免责声明