Summary
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- age <3 years
- leukocoria (white pupillary reflex)
- strabismus
- positive family history
- orbital pseudocellulitis
- 13q syndrome
Другие диагностические факторы
- visual disturbances
- ocular pain
- pinealoma
Факторы риска
- mutation in RB1 gene
- human papillomavirus (HPV) exposure
- advanced paternal age
Диагностические исследования
Исследования, которые показаны в первую очередь
- funduscopy and examination under anesthesia
- wide-field fundus photography and spectral domain optical coherence tomography (sdOCT)
- ophthalmic A- and B-scan ultrasound
Исследования, проведение которых нужно рассмотреть
- genetic testing
- MRI head/orbit
- bone marrow aspiration
- lumbar puncture
Неотложные исследования
- liquid biopsy
Алгоритм лечения
with vitreous seeding
without vitreous seeding
metastatic disease
recurrence
Составители
Авторы
Timothy G. Murray, MD, MBA, FACS
Founding Director/CEO
Murray Ocular Oncology and Retina
Miami
FL
Раскрытие информации
TGM is an author of a number of references cited in this topic.
Victor M. Villegas, MD
Ocular Oncologist
Associate Professor
Department of Ophthalmology
University of Puerto Rico
Associate Professor
Department of Surgery
Ponce Health Sciences University School of Medicine
Voluntary Faculty
Bascom Palmer Eye Institute
University of Miami
Miami
FL
Раскрытие информации
VMV is an author of a reference cited in this topic.
Выражение благодарностей
Dr Timothy G. Murray and Dr Victor M. Villegas would like to gratefully acknowledge Dr Amy C. Schefler, a previous contributor to this topic, and Dr Steven Houston, III, MD for his contribution to the topic.
Раскрытие информации
ACS is an author of a number of references cited in this topic. SH declares that he has no competing interests.
Рецензенты
Susan Schneider, MD
Director
Pharmaceutical Clinical & Scientific Affairs
Bausch & Lomb
Rochester
NY
Раскрытие информации
SS declares that she has no competing interests.
Francis Munier, MD
Professor and Head of Pediatric Ocular Oncology Unit
Jules Gonin Eye Hospital
Lausanne
Switzerland
Раскрытие информации
FM declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
Kamihara J, Bourdeaut F, Foulkes WD, et al. Retinoblastoma and neuroblastoma predisposition and surveillance. Clin Cancer Res. 2017 Jul 1;23(13):e98-106.Полный текст Аннотация
Global Retinoblastoma Study Group. The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries. Lancet Glob Health. 2022 Aug;10(8):e1128-40.Полный текст Аннотация
Skalet AH, Gombos DS, Gallie BL, et al. Screening children at risk for retinoblastoma: consensus report from the American Association of Ophthalmic Oncologists and Pathologists. Ophthalmology. 2018 Mar;125(3):453-8.Полный текст Аннотация
de Graaf P, Goricke S, Rodjan F, et al. Guidelines for imaging retinoblastoma: imaging principles and MRI standardization. Pediatr Radiol. 2012 Jan;42(1):2-14.Полный текст Аннотация
American College of Radiology. ACR appropriateness criteria: orbits, vision and visual loss. 2017 [internet publication].Полный текст Аннотация
Hutchinson AK, Morse CL, Hercinovic A, et al. Pediatric eye evaluations preferred practice pattern. Ophthalmology. 2023 Mar;130(3):P222-70.Полный текст Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Отличия
- Coats disease (exudative retinitis or retinal telangiectasis)
- Persistent fetal vasculature (formerly known as persistent hyperplastic primary vitreous)
- Retinopathy of prematurity (ROP)
Больше ОтличияРекомендации
- Pediatric eye evaluations preferred practice pattern
- Screening children at risk for retinoblastoma
Больше Рекомендации
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