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Hiccups

Última revisão: 9 Dec 2025
Última atualização: 12 Jan 2023

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • "hic" sound
Detalhes completos

Outros fatores diagnósticos

  • duration <48 hours (typically benign hiccups)
  • duration >48 hours (chronic hiccups)
  • persistence during sleep
  • associated features of underlying cause
  • weight loss and malnutrition
Detalhes completos

Fatores de risco

  • aerophagia, temperature changes, and emotional states
  • diaphragmatic and phrenic nerve irritation
  • vagus nerve irritation
  • central nervous system disorders
  • metabolic/electrolyte abnormalities
  • toxins/drugs
  • psychogenic disorders
  • sedation or anesthesia
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • clinical diagnosis
Detalhes completos

Investigações a serem consideradas

  • CBC
  • serum electrolytes
  • BUN
  • C-reactive protein and erythrocyte sedimentation rate
  • liver function tests
  • gamma glutamyl transpeptidase (gamma-GT)
  • serum amylase
  • toxicology screen
  • arterial blood gas
  • ECG
  • chest x-ray
  • pulmonary function tests
  • CT abdomen
  • endoscopy of the upper gastrointestinal tract
  • CT or MRI head
  • lumbar puncture
  • otoscopy
  • pharyngoscopy
Detalhes completos

Algoritmo de tratamento

AGUDA

benign hiccups

CONTÍNUA

chronic hiccups

Colaboradores

Autores

Aminah Jatoi, MD

Professor of Oncology

Department of Oncology

Mayo Clinic

Rochester

MN

Declarações

AJ has received a grant review for Pfizer (money is paid to her institution) and research funding from AstraZeneca. AJ is on an advisory board for Meter Health and Novartis. AJ is an author of one reference cited in this topic.

Agradecimentos

Professor Aminah Jatoi would like to gratefully acknowledge Professor Peter Kranke, Dr Yvonne Jelting, and Dr Thomas M. Metterlein, previous contributors to this topic.

Declarações

PK is an author of a reference cited in this topic. YJ and TMM declare that they have no competing interests.

Revisores

Andy Smith, BM, BS, MRCP, FRCA

Consultant Anaesthetist and Associate Director of Research and Development

Director

Lancaster Patient Safety Research Unit

Royal Lancaster Infirmary

Lancaster

UK

Declarações

AS declares that he has no competing interests.

Stefan K. Burgdorf, MD

Registrar

Department of Surgical Gastroenterology

Herlev Hospital

University of Copenhagen

Denmark

Declarações

SKB declares that he has no competing interests.

Howard Smith, MD, FACP

Academic Director of Pain Management

Associate Professor of Anesthesiology

Department of Anesthesiology

Albany Medical College

Albany

NY

Declarações

HS is an author of a reference cited in this topic.

Créditos aos pareceristas

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Referências

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Principais artigos

Lewis JH. Hiccups: causes and cures. J Clin Gastroenterol. 1985 Dec;7(6):539-52. Resumo

Wagner MS, Stapczynski JS. Persistent hiccups. Ann Emerg Med. 1982 Jan;11(1):24-6. Resumo

Rousseau P. Hiccups. South Med J. 1995 Feb;88(2):175-81. Resumo

Moretto EN, Wee B, Wiffen PJ, et al. Interventions for treating persistent and intractable hiccups in adults. Cochrane Database Syst Rev. 2013 Jan 31;(1):CD008768.Texto completo  Resumo

Zhu LL, Wang WX, Guo XG. Acupuncture for hiccups after stroke: a systematic review. Chin J Evid Based Med. 2011;11:325-8.

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.

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