Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- motion stimulus for symptoms
- epigastric discomfort
- nausea
- headache
- vomiting
Other diagnostic factors
- cold sweating
- dry mouth
- dizziness
- yawning and sleepiness
- pallor
- unsteadiness and incoordination
Risk factors
- childhood age
- female sex
- Asian ancestry
- family history of motion sickness
- history of migraine
- vestibulopathy
- visual disorder
- smoking
- spatial disorientation and space-motion discomfort syndromes
- hormonal factors
- unpleasant odours/sight or smell of vomit
- conflicting sensory inputs (e.g., reading in car, tilting trains)
- psychological factors
- spatially loaded concurrent tasks
- neurological disorder
Diagnostic investigations
1st investigations to order
- clinical diagnosis
Treatment algorithm
anticipated motion sickness
unanticipated motion sickness
known susceptibility
Contributors
Authors
Amir Kheradmand, MD
Associate Professor
Department of Neurology, Neuroscience, Otolaryngology-Head and Neck Surgery, and Laboratory for Computational Sensing and Robotics (LCSR)
John Hopkins University School of Medicine
Baltimore
MD
Disclosures
AK is the author of references cited in this topic.
Qadeer Arshad, PhD
Associate Professor
inAmind Laboratory, College of Life Sciences
University of Leicester
Leicester
UK
Disclosures
QA is the author of references cited in this topic.
Acknowledgements
Dr Amir Kheradmand and Dr Qadeer Arshad would like to gratefully acknowledge Dr Kenneth L. Koch and Dr Michael A. Gresty, the previous contributors to this topic.
Disclosures
KLK and MAG are authors of several references cited in this topic.
Peer reviewers
Alan J. Benson, MB, ChB
Visiting Consultant to the Royal Air Force Centre for Aviation Medicine
Royal Air Force Henlow
UK
Disclosures
AJB declares that he has no competing interests.
David Andrew Green, PhD
Lecturer in Human Cardiorespiratory and Aerospace Physiology
Division of Applied Biomedical Research
Department of Physiology
King's College London
London
UK
Disclosures
DAG declares that he has no competing interests.
Michael von Brevern, MD, PhD
Department of Neurology
Park-Klinik Weissensee
Berlin
Germany
Disclosures
MVB declares that he has no competing interests.
Richard Lewis, MD
Associate Professor
Otolaryngology and Neurology
Harvard Medical School
Boston
MA
Disclosures
RL declares that he has no competing interests.
Differentials
- Migraine
- Food poisoning
- Acute vestibular disorder
More DifferentialsGuidelines
- CDC Yellow Book: health information for international travel - motion sickness
- Motion sickness diagnostic criteria: consensus document of the Classification Committee of the Bárány Society
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