Nausea and vomiting in pregnancy

Nausea and vomiting in pregnancy (NVP) affects approximately 75% of pregnant women.

Typically begins between the fourth and eighth week after the last menstrual period and resolves in the second trimester.

Aetiology remains unclear. There is some evidence that it is related to hormone levels of human chorionic gonadotrophin and oestrogen.

Hyperemesis gravidarum represents the most severe form of NVP. While there is lack of consensus of definition, most agree that clinical features include persistent vomiting, volume depletion, ketosis, electrolyte disturbances, and weight loss.

Initial therapy should be conservative. This may include non-pharmacological treatments such as diet modification, emotional support, ginger, and acupressure.

Severe cases may require hospitalisation, intravenous fluids, anti-emetics, corticosteroids, and parenteral nutrition.

Nausea and vomiting in pregnancy (NVP), commonly referred to as morning sickness, typically begins between the fourth and eighth week after the last menstrual period. It is characterised by nausea and vomiting that occur more frequently during the morning hours, and typically resolves in the second trimester. Hyperemesis gravidarum is the most severe form of NVP and is characterised by persistent vomiting, volume depletion, ketosis, electrolyte disturbances, and weight loss.