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Frostbite

Evidence last reviewed: 3 Sep 2026
Topic last updated: 02 Dec 2024

Summary

Definition

History and exam

Key diagnostic factors

  • cold or numbness of affected extremity
  • pain during rewarming
  • purplish skin discoloration
  • white or yellowish, waxy skin discoloration
  • superficial skin vesiculation
  • deep purple blisters
  • tissue necrosis and mummification (dry gangrene)
Full details

Other diagnostic factors

  • erythema
  • joint dislocation
  • fractures
Full details

Risk factors

  • cold exposure
  • previous frostbite
  • vascular insufficiency
  • high altitude
  • hypoxia
  • alcohol
  • tobacco
  • dehydration
  • extremity trauma
  • constrictive clothing or equipment
Full details

Diagnostic tests

1st tests to order

  • clinical diagnosis
Full details

Tests to consider

  • technetium-99m pertechnetate scintigraphy
  • magnetic resonance angiography of affected extremity
  • plain radiography
Full details

Emerging tests

  • thermography and duplex imaging

Treatment algorithm

ACUTE

all patients

Contributors

Authors

Elizabeth A. Kaufman, MD, CAQ-SM

Attending Physician

Department of Orthopedics, Sports Medicine

Scripps Clinic

Attending Physician

Rady Children’s Hospital San Diego

Department of Orthopedics, Sports Medicine

San Diego

CA

Disclosures

EAK declares that she has no competing interests.

Christopher Imray, PhD, FRCS, FRCP, FRGS

Consultant Vascular and Renal Transplant Surgeon

University Hospital Coventry and Warwickshire NHS Trust

Professor Coventry University, Warwick Medical School, Exeter University

Coventry

UK

Disclosures

CI has been asked to provide expert testimony on frostbite. He has delivered lectures, and produced educational material on frostbite.

Acknowledgements

Professor Christopher Imray and Dr Elizabeth A. Kaufman would like to gratefully acknowledge Professor Paul S. Auerbach and Dr Claire Turchi, previous contributors to this topic. PSA and CT declare that they have no competing interests.

Revisores por pares

Luanne Freer, MD, FACEP, FAWM

Medical Director

Yellowstone National Park

WY

Founder/Director

Everest Base Camp Medical Clinic

Nepal

Divulgaciones

LF declares that she has no competing interests.

Grant S. Lipman, MD

Clinical Assistant Professor of Surgery and Emergency Medicine

Associate Director Wilderness Medicine Fellowship

Assistant Research Director

Stanford University School of Medicine

Palo Alto

CA

Divulgaciones

GSL declares that he has no competing interests.

Peter Hackett, MD

Director

Institute for Altitude Medicine

Telluride

CO

Divulgaciones

PH declares that he has no competing interests.

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Referencias

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Artículos principales

McIntosh SE, Freer L, Grissom CK, et al. Wilderness Medical Society clinical practice guidelines for the prevention and treatment of frostbite: 2024 update. Wilderness Environ Med. 2024 Jun;35(2):183-97.Texto completo  Resumen

Sheridan RL, Goverman JM, Walker TG. Diagnosis and treatment of frostbite. N Engl J Med. 2022 Jun 9;386(23):2213-20.

Rabold MB. Frostbite and other localized cold-related injuries. In: Tintinalli JE, Kelen GD, Stapczynski JS, et al. Tintinalli's emergency medicine: a comprehensive study guide. 6th ed. New York, NY: McGraw-Hill; 2004.

Roche-Nagle G, Murphy D, Collins A, et al. Frostbite: management options. Eur J Emerg Med. 2008 Jun;15(3):173-5. Resumen

Artículos de referencia

Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
  • Frostbite images
  • Diferenciales

    • Cutaneous burns
    • Frostnip
    • Raynaud phenomenon
    Más Diferenciales
  • Guías de práctica clínica

    • 2024 American Heart Association and AmericanRed Cross Guidelines for First Aid
    • Clinical practice guidelines for the prevention and treatment of frostbite: 2024 update
    Más Guías de práctica clínica
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