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Dry eye disease

Última revisão: 14 Jul 2025
Última atualização: 19 Jun 2025

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • known underlying medical cause
  • use of known causative medications
  • corneal filaments
Detalhes completos

Outros fatores diagnósticos

  • ocular irritation/foreign body sensation
  • ocular burning
  • transient blurred vision
  • tearing
  • blepharitis/meibomianitis
  • punctate epithelial erosions
  • conjunctival punctate erosions
  • conjunctival injection
  • lagophthalmos
  • proptosis
  • presence of mites
Detalhes completos

Fatores de risco

  • female sex
  • older age
  • blepharitis/meibomianitis
  • connective tissue disorders
  • vitamin A deficiency
  • hepatitis C
  • HIV
  • hematopoietic stem cell transplantation
  • lens and eyelid surgery
  • contact lens use
  • diabetes mellitus
  • systemic medications
  • preserved topical ophthalmic medications
  • sarcoidosis
  • Parkinson disease
  • environmental factors
  • occupational factors
  • headache
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • tear film meniscus height (meniscometry)
  • tear film/fluorescein breakup time (TFBUT)
  • Schirmer test
Detalhes completos

Novos exames

  • tear film osmometry
  • metalloproteinase-9 (MMP-9) detection
  • corneal topography
  • ocular surface interferometry
  • infrared thermography
  • in-vivo confocal microscopy
  • ocular surface immune markers (OSIM)

Algoritmo de tratamento

AGUDA

dry eye at initial presentation

CONTÍNUA

chronic dry eye

Colaboradores

Autores

Jonathan Smith, FRCOphth, MRCP

Consultant Ophthalmologist

Sunderland Eye Infirmary

Sunderland

UK

Declarações

JS declares that he has no competing interests.

Philip Severn, FRCOphth, MRCP

Consultant Ophthalmologist

James Cook University Hospital

Middlesbrough

UK

Declarações

PS declares that he has served on the advisory boards of and received travel grants from Bayer and Novartis. He has also received travel grants from Allergan.

Darren Shu Jeng Ting, FRCOphth, PhD

Honorary Associate Professor of Ophthalmology

School of Medicine

University of Nottingham

Consultant Ophthalmologist

Birmingham and Midland Eye Centre

UK

Declarações

DSJT declares that he has no competing interests.

Saurabh Ghosh, FRCOphth

Consultant Ophthalmologist

Sunderland Eye Infirmary

Sunderland

UK

Declarações

SG declares that he has no competing interests.

Revisores

I-Hui Wu, MD

Ophthalmology Resident

Wilmer Eye Institute

Baltimore

MD

Declarações

IW declares that she has no competing interests.

Gus Gazzard, MA, MBBChir, MD, FRCOphth

Consultant Ophthalmic Surgeon

King's College Hospital

Honorary Research Fellow

Institute of Ophthalmology

London

UK

Declarações

GG declares that he has no competing interests.

Bob Avery, MD, PhD

Assistant Professor

Ophthalmology

University of New Mexico Medical School

Albuquerque

NM

Declarações

BA declares that he has no competing interests.

Vatinee Y. Bunya, MD

Co-Director

Penn Dry Eye and Ocular Surface Center

Assistant Professor

Cornea and External Disease

Scheie Eye Institute

Philadelphia

PA

Declarações

VYB declares that she has no competing interests.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

Hakim FE, Farooq AV. Dry eye disease: an update in 2022. JAMA. 2022 Feb 1;327(5):478-9. Resumo

Amescua G, Ahmad S, Cheung AY, et al. Dry eye syndrome preferred practice pattern®. Ophthalmology. 2024 Apr;131(4):P1-49.Texto completo  Resumo

Craig JP, Nichols KK, Akpek EK, et al. TFOS DEWS II definition and classification report. Ocul Surf. 2017 Jul;15(3):276-83.Texto completo  Resumo

Shtein RM, Shen JF, Kuo AN, et al. Autologous serum-based eye drops for treatment of ocular surface disease: a report by the American Academy of Ophthalmology. Ophthalmology. 2020 Jan;127(1):128-33.Texto completo  Resumo

Artigos de referência

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