Summary
Definition
History and exam
Key diagnostic factors
- identification of the snake
- local redness, swelling, tenderness, and pain at wound site
- blurred or double vision
- shortness of breath
- difficulty swallowing
- hypotension
- tachypnea
- tachycardia
- puncture marks, fang marks
- bulbar weakness/paralysis
- stridor
- hemorrhage
- quadriplegia/locked-in syndrome
Other diagnostic factors
- nausea and vomiting
- malaise, generalized weakness or dizziness
- perioral tingling or numbness
- urticaria
- tremors
Risk factors
- male sex
- alcohol consumption
- intentional snake encounter
Diagnostic tests
1st tests to order
- prothrombin time, PTT, fibrinogen, and D-dimer
- CBC
- electrolytes, BUN, and creatinine
- arterial blood gas
- creatine kinase (CK)
- lactate
- urinalysis
- ECG
- chest x-ray
- wound x-ray
- negative inspiratory force (NIF) test
Tests to consider
- CT/MRI
- compartment pressure
- central venous line with central venous pressure (CVP) transduction
- arterial line with pressure transduction
Treatment algorithm
presumed snakebite
confirmed snakebite
Contributors
Authors
David Vearrier, MD, MPH, FAAEM, FACMT, FAACT
Professor of Emergency Medicine
Division of Medical Toxicology
Department of Emergency Medicine
Associate Program Director, Preventive Medicine Residency
Co-Director, Student and Employee Health
Department of Preventive Medicine
University of Mississippi Medical Center
Jackson
MS
Disclosures
DV declares that he has no competing interests.
Acknowledgements
Prof. David Vearrier would like to gratefully acknowledge Prof. Michael Greenberg, previous contributor to this topic. MG declared that he had no competing interests.
Peer reviewers
Scott Phillips, MD
Associate Clinical Professor of Medicine
Department of Clinical Pharmacology and Toxicology
University of Colorado
Health Science Center
Denver
CO
Disclosures
SP has a professional relationship with Michael Greenberg, one of the original contributors to this topic. They are partners in a private consulting company. SP does not receive money from him, nor does he receive money from SP.
Donna Seger, MD
Medical Director TN Poison Center
Associate Professor of Medicine and Emergency Medicine
Vanderbilt University Medical Center
Nashville
TN
Disclosures
DS declares that she has no competing interests.
Senanayake Kularatne, MBBS, MD, MRCP, FRCP, FCCP
Professor
Department of Medicine
Peredeniya University
Sri Lanka
Disclosures
SK declares that he has no competing interests.
Differentials
- Anaphylaxis
More DifferentialsGuidelines
- Part 15: First aid. 2015 American Heart Association and American Red Cross guidelines update for first aid
- Wilderness Medical Society practice guidelines for the treatment of pitviper envenomations in the US and Canada
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