Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- history of residence in, or recent travel to, endemic area
- lack of yellow fever immunization
- history of mosquito bite
- fever
- constitutional symptoms
- conjunctival injection
- relative bradycardia (Faget sign)
- biphasic illness
- hemorrhagic diathesis
- signs of renal failure
- signs of hepatic failure
- jaundice
Outros fatores diagnósticos
- hypotension
- abdominal pain, vomiting, and lethargy
Fatores de risco
- residence in, or recent travel to, endemic area
- lack of immunization
- mosquito bite
- travel during rainy and early dry seasons
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- CBC
- liver function tests
- coagulation screen
- reverse transcription polymerase chain reaction (RT-PCR)
- serology
Investigações a serem consideradas
- ECG
- histopathology
Novos exames
- virus isolation
- isothermal nucleic acid amplification assays
Algoritmo de tratamento
unidentified viral hemorrhagic fever
confirmed yellow fever
Colaboradores
Autores
William A. Messer, MD, PhD
Associate Professor of Medicine
Department of Molecular Microbiology and Immunology
Division of Infectious Diseases
Oregon Health & Science University
Portland
OR
Declarações
WAM declares that he has no competing interests.
Agradecimentos
Dr William A. Messer would like to gratefully acknowledge Dr Philip A. Yeon and Dr Helmut Albrecht, previous contributors to this topic.
Disclosures
PAY and HA declares that he has no competing interests.
Revisores
Carlos Franco-Paredes, MD, MPH
Assistant Professor
Emory University
TravelWell Clinic
Emory University Hospital Midtown
Atlanta
GA
Declarações
CFP declares that he has no competing interests.
Andrea K. Boggild, MSc, MD, DTMH, FRCPC
Clinical Assistant
Tropical Diseases Unit
Division of Infectious Diseases
Department of Medicine
Toronto General Hospital
University Health Network
Toronto
Canada
Declarações
AKB declares that she has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referências
Principais artigos
World Health Organization. Yellow fever: fact sheet. May 2023 [internet publication].Texto completo
Staples JE, Bocchini JA Jr, Rubin L; Centers for Disease Control and Prevention (CDC). Yellow fever vaccine booster doses: recommendations of the Advisory Committee on Immunization Practices, 2015. MMWR Morb Mortal Wkly Rep. 2015;64:647-650.Texto completo Resumo
Pan American Health Organization; World Health Organization. Laboratory diagnosis of yellow fever virus infection. September 2018 [internet publication].Texto completo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
Diagnósticos diferenciais
- Dengue fever
- Malaria
- Zika virus infection
Mais Diagnósticos diferenciaisDiretrizes
- CDC Yellow Book: health information for international travel - yellow fever
- Laboratory diagnosis of yellow fever virus infection
Mais Diretrizes
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