Summary
Definition
History and exam
Key diagnostic factors
- nausea/vomiting
- diarrhea
- fever
Other diagnostic factors
- myalgias
- headache
- abdominal tenderness
- signs of volume depletion
- hyperactive bowel sounds
- family history of Salmonella infection
Risk factors
- food exposures
- extremes of age (<12 months and >50 years)
- presence of an immunosuppressive state
- low gastric acidity
- exposure to symptomatic person with Salmonella
- animal contact
- use of antibiotics
- poorly controlled diabetes mellitus
- chronic granulomatous disease
- iron overload
- malnutrition
Diagnostic investigations
1st investigations to order
- stool studies
Investigations to consider
- blood cultures
- imaging studies
Treatment algorithm
gastroenteritis
chronic carrier state
Contributors
Authors
Ferric C. Fang, MD
Professor of Laboratory Medicine, Pathology, and Microbiology
Adjunct Professor of Medicine (Infective Diseases)
University of Washington School of Medicine
Seattle
WA
Disclosures
FCF is a consultant for bioMérieux and a member of the SaNOtize scientific advisory board, and an author of references cited in this topic.
Acknowledgements
Dr Ferric C. Fang would like to gratefully acknowledge Dr William A. Petri, Dr Michael Preziosi, Dr Joshua Fierer, and Dr Nancy F. Crum-Cianflone, previous contributors to this topic.
Disclosures
JF and NFCC are authors of references cited in this topic. WAP and MP declare that they have no competing interests.
Peer reviewers
David Acheson, MD
Chief Medical Officer
Director of Food Safety and Security
US Food and Drug Administration
Rockville
MD
Declarações
DA declares that he has no competing interests.
Timothy Jones, MD
Deputy State Epidemiologist
Communicable and Environmental Disease Services
Tennessee Department of Health
Nashville
TN
Declarações
TJ declares that he has no competing interests.
Franz Allerberger, MD, MPH
Head of Division
Division for Public Health
Austrian Agency for Health & Food Safety
Vienna
Austria
Declarações
FA declares that he has no competing interests.
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Referências
Principais artigos
Delahoy MJ, Shah HJ, Weller DL, et al. Preliminary incidence and trends of infections caused by pathogens transmitted commonly through food - foodborne diseases active surveillance network, 10 U.S. sites, 2022. MMWR Morb Mortal Wkly Rep. 2023 Jun 30;72(26):701-6.Texto completo Resumo
Pegues DA, Miller SI. Salmonella species, including Salmonella Typhi. In: Mandell, Douglas, and Bennett's principles and practice of infectious diseases. 7th ed. Philadelphia, PA: Churchill Livingstone; 2010:2887-903.
Shane AL, Mody RK, Crump JA, et al. 2017 Infectious Diseases Society of America clinical practice guidelines for the diagnosis and management of infectious diarrhea. Clin Infect Dis. 2017 Nov 29;65(12):1963-73.Texto completo Resumo
Riddle MS, DuPont HL, Connor BA. ACG Clinical guideline: diagnosis, treatment, and prevention of acute diarrheal infections in adults. Am J Gastroenterol. 2016 May;111(5):602-22. Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
Diagnósticos diferenciais
- Shigellosis
- Campylobacter species infection
- Yersiniosis
Mais Diagnósticos diferenciaisDiretrizes
- 2017 Infectious Disease Society of America clinical practice guidelines for the diagnosis and management of infectious diarrhea
- Compendium of measures to prevent disease associated with animals in public settings
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