Summary
Differentials
Common
- Allergy to food or drug
- Insect bites or stings
- Adverse drug reaction to, e.g., antibiotic, anticonvulsant, or allopurinol
- Chemotherapy
- Enterovirus and echovirus infection
- Fifth disease (erythema infectiosum)
- Roseola infantum (sixth disease)
- Epstein Barr virus (EBV) infection (infectious mononucleosis)
- Cytomegalovirus (CMV) infection
Uncommon
- Iodinated contrast media non-immediate adverse reaction
- Erythema multiforme major (toxic epidermal necrolysis or Stevens-Johnson syndrome)
- Drug reaction with eosinophilia and systemic symptoms
- Erythema multiforme
- Systemic hypersensitivity syndrome
- HIV-seroconversion exanthema
- Acute hepatitis B virus infection
- Acute hepatitis C virus infection
- Rubella (German measles)
- Rubeola (measles)
- Meningococcaemia
- Scarlet fever
- Staphylococcal scalded skin syndrome
- Toxic shock syndrome (Staphylococcus exotoxin)
- Rocky Mountain spotted fever or Mediterranean spotted fever
- Acute graft-versus-host disease
- Kawasaki disease (mucocutaneous lymph node syndrome)
- Juvenile-onset or adult-onset Still disease
- Syphilis (secondary)
- Ebola virus infection
- Zika virus infection
- Chikungunya virus infection
- Dengue fever
Contributors
Authors
Professor & Director of Pediatric Dermatology
Department of Dermatology and Pediatrics
UTHealth McGovern Medical School Houston
Houston
TX
Disclosures
AAH declares that she has no competing interests
Clinical Research Fellow
Department of Dermatology
University of Texas Health Sciences Center in Houston
Houston
TX
Disclosures
QN declares that she has no competing interests.
Dr Adelaide A. Hebert and Dr Quoc-Bao Nguyen would like to gratefully acknowledge Dr Mary DarConte, Dr Mark Naftanel, and Dr Hobart W. Walling, previous contributors to this topic.
Disclosures
MD, MN, and HWW declare that they have no competing interests.
Peer reviewers
Clinical Assistant Professor
University of Iowa College of Medicine
Iowa City
IA
Disclosures
BS declares that he has no competing interests.
Dermatologist
Town Square Dermatology
Coralville
IA
Disclosures
KS declares that she has no competing interests.
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