Meningioma

Meningioma is a predominantly nonmalignant tumor of the meninges occurring at both cranial and spinal sites.

Can be asymptomatic or cause symptoms from local mass effect due to compression of neural structures.

Diagnosis is confirmed by the characteristic appearance on magnetic resonance imaging (MRI) with and without contrast enhancement.

Asymptomatic lesions may be followed up with serial observation. Treatment options for symptomatic meningiomas include surgical resection, which provides pathologic diagnosis, and radiation therapy.

Recurrent meningiomas may be treated with salvage therapy.

Meningiomas are the most common primary tumor of the cranial and spinal compartments and are predominantly nonmalignant (World Health Organization [WHO] grades 1 and 2). Malignant WHO grade 3 tumors are rare. Tumors of the cerebral meninges are significantly more common than those of the spinal meninges.[1]Ostrom QT, Price M, Neff C, et al. CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2016-2020. Neuro Oncol. 2023 Oct 4;25(12 suppl 2):iv1-99. https://academic.oup.com/neuro-oncology/article/25/Supplement_4/iv1/7289107 http://www.ncbi.nlm.nih.gov/pubmed/37793125?tool=bestpractice.com