Last reviewed:December 2019
Last updated:January  2018

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • jaundice
  • pallor
  • dark urine

Risk factors

  • male sex
  • neonate
  • ethnic origin in the Mediterranean, sub-Saharan Africa, Middle East, or Southeast Asia
  • family history
  • recent exposure to oxidative drugs
  • infection
  • recent exposure to broad beans (favism)

Diagnostic investigations

Treatment algorithm

Contributors

Professor of Haematology and Consultant Haematologist

Royal Free Hospital and University College London School of Medicine

London

UK

Disclosures

ABM declares that he has no competing interests.

Peer reviewersVIEW ALL

Professor of Hematology

University of Firenze

Florence

Italy

Disclosures

LL declares that he has no competing interests.

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