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Abusive head trauma in infants and young children

Last reviewed: 9 Apr 2025
Last updated: 22 Mar 2024

Summary

Definition

History and exam

Key diagnostic factors

  • age <3 years
  • altered mental status: irritability/lethargy/coma
  • clinical findings inconsistent with carer history
  • retinal/vitreal hemorrhages or retinoschisis
  • apnea
Full details

Other diagnostic factors

  • no known history of trauma
  • seizure
  • vomiting
  • loss of muscle tone
  • brisk or asymmetric reflexes
  • unexplained bruising
  • increasing head circumference
  • bulging fontanelle
  • long-bone fractures
  • mucosal injury or torn labial/lingual frenulum
  • anogenital signs and symptoms
Full details

Risk factors

  • age <1 year
  • peak of normal crying curve
  • male caregiver
  • unrelated adult household member
  • male sex
  • socioeconomic stressors
Full details

Diagnostic tests

1st tests to order

  • cranial CT scan
  • CBC
  • liver function tests
  • toxicology screen
  • prothrombin time (PT)/activated PTT/fibrinogen/von Willebrand testing
  • urinalysis
  • cerebrospinal fluid analysis
  • cranial MRI
Full details

Tests to consider

  • spinal MRI
  • cranial ultrasound
  • skeletal survey
  • complementary imaging
  • blood culture
  • serum calcium
  • serum 1,25-dihydroxy vitamin D levels (calcidiol)
  • serum inorganic phosphorus
  • serum parathyroid hormone (PTH)
  • serum alkaline phosphatase
  • skin biopsy/fibroblast culture
  • postmortem exam
Full details

Treatment algorithm

ACUTE

all patients

Contributors

Authors

Barney Scholefield, MBBS, BSc, MSc, MRCPCH, PhD

Consultant in Paediatric Intensive Care

NIHR Clinician Scientist

Birmingham Women’s and Children’s NHS Foundation Trust

Birmingham

UK

Disclosures

BS receives grant funding from the UK NIHR Clinician Scientist Fellowship programme.

Acknowledgements

Dr Barney Scholefield would like to gratefully acknowledge Dr Joe Brierley, Dr Gavin Wooldridge, and Dr Alice Newton, previous contributors to this topic.

Disclosures

JB, GW, and AN declare that they have no competing interests.

Peer reviewers

Amy Goldberg, MD

Attending Physician

Child Protection Team

Hasboro Children's Hospital

Assistant Professor of Pediatrics

Alpert Medical School

Brown University

Providence

RI

Disclosures

AG declares that she has no competing interests.

Rebecca Moles, MD

Division Chief

Child Protection Program

UMass Memorial Medical Center

Worcester

MA

Disclosures

RM declares that she has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Narang SK, Fingarson A, Lukefahr J; Council on Child Abuse and Neglect. Abusive head trauma in infants and children. Pediatrics. 2020 Apr;145(4):e20200203.Full text  Abstract

Nuño M, Pelissier L, Varshneya K, et al. Outcomes and factors associated with infant abusive head trauma in the US. J Neurosurg Pediatr. 2015 Nov;16(5):515-22.Full text  Abstract

National Institute for Health and Care Excellence (UK). Child maltreatment: when to suspect maltreatment in under 18s. October 2017 [internet publication].Full text

Piteau SJ, Ward MG, Barrowman NJ, et al. Clinical and radiographic characteristics associated with abusive and nonabusive head trauma: a systematic review. Pediatrics. 2012 Aug;130(2):315-23. Abstract

Christian CW, Levin AV, Committee on Child Abuse and Neglect, et al. The eye examination in the evaluation of child abuse. Pediatrics. 2018 Aug;142(2):e20181411.Full text  Abstract

American College of Radiology. Practice parameter for the performance and interpretation of skeletal surveys in children. 2021 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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