Hand-foot-and-mouth disease
Resumen
Definición
Anamnesis y examen
Principales factores de diagnóstico
- low-grade fever
- oral vesicles and ulcers
- rash and/or vesicles on the hands and feet
Otros factores de diagnóstico
- malaise
- sore mouth
- loss of appetite
- sore throat
- rash and/or vesicles on the buttocks
- abdominal pain
- diarrhea
- cough
- tongue erythema/edema
- arthralgia
Factores de riesgo
- immunosuppression
- age <10 years
- family or school contacts with infection
Pruebas diagnósticas
Pruebas diagnósticas que deben considerarse
- viral culture
- CBC
Pruebas emergentes
- PCR molecular assays
Algoritmo de tratamiento
all patients
Colaboradores
Autores
Malobi I. Ogboli, MBBS, FRCP
Consultant Dermatologist
Birmingham Children's Hospital and Birmingham City Hospital
Birmingham
UK
Divulgaciones
MIO declares that she has no competing interests.
Revisores por pares
Helen Goodyear, MBChB, MRCP, FRCPCH, MD, MMed
Consultant Paediatrician
Heartlands Hospital
Birmingham
UK
Divulgaciones
HG declares that she has no competing interests.
Andrew Riordan, MD, FRCPCH, MRCP, DTM&H
Consultant in Paediatric Infectious Diseases and Immunology
Royal Liverpool Children's Hospital (Alder Hey)
Liverpool
UK
Divulgaciones
AR declares that he has no competing interests.
David Cassarino, MD, PhD
Assistant Professor
Department of Pathology and Laboratory Medicine
University of California
Los Angeles
CA
Divulgaciones
DC declares that he has no competing interests.
Leonid Izikson, MD
Staff Dermatologist
Department of Dermatology
Massachusetts General Hospital
Boston
MA
Divulgaciones
LI declares that he has no competing interests.
Aisha Sethi, MD
Assistant Professor of Medicine
Associate Residency Program Director
University of Chicago
Chicago
IL
Divulgaciones
AS declares that she has no competing interests.
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Divulgaciones
Las afiliaciones y divulgaciones de los revisores por pares se refieren al momento de la revisión.
Referencias
Artículos principales
Alsop J, Flewett TH, Foster JR. "Hand-foot-and-mouth disease" in Birmingham in 1959. Br Med J. 1960;2:1708-1711.Texto completo Resumen
Ishimaru Y, Nakano S, Yamaoka K, et al. Outbreaks of hand, foot, and mouth disease by enterovirus 71. High incidence of complication disorders of central nervous system. Arch Dis Child. 1980;55:583-588.Texto completo Resumen
Saguil A, Kane SF, Lauters R, et al. Hand-foot-and-mouth disease: rapid evidence review. Am Fam Physician. 2019 Oct 1;100(7):408-14.Texto completo Resumen
Chang LY, Tsao KC, Hsia SH, et al. Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan. JAMA. 2004;291:222-227.Texto completo Resumen
Chang LY, Lin TY, Huang YC, et al. Comparison of enterovirus 71 and coxsackie-virus A16 clinical illnesses during the Taiwan enterovirus epidemic, 1998. Pediatr Infect Dis J. 1999;18:1092-1096. Resumen
Artículos de referencia
Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
Differentials
- Aphthous stomatitis or oral aphthous ulcers
- Herpes simplex
- Herpangina
Más DiferencialesGuidelines
- A guide to clinical management and public health response for hand, foot and mouth disease (HFMD)
Más Guidelines
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