Резюме
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- low-grade fever
- oral vesicles and ulcers
- rash and/or vesicles on the hands and feet
Другие диагностические факторы
- malaise
- sore mouth
- loss of appetite
- sore throat
- rash and/or vesicles on the buttocks
- abdominal pain
- diarrhea
- cough
- tongue erythema/edema
- arthralgia
Факторы риска
- immunosuppression
- age <10 years
- family or school contacts with infection
Диагностические исследования
Исследования, проведение которых нужно рассмотреть
- viral culture
- CBC
Неотложные исследования
- PCR molecular assays
Алгоритм лечения
all patients
Составители
Авторы
Malobi I. Ogboli, MBBS, FRCP
Consultant Dermatologist
Birmingham Children's Hospital and Birmingham City Hospital
Birmingham
UK
Раскрытие информации
MIO declares that she has no competing interests.
Рецензенты
Helen Goodyear, MBChB, MRCP, FRCPCH, MD, MMed
Consultant Paediatrician
Heartlands Hospital
Birmingham
UK
Раскрытие информации
HG declares that she has no competing interests.
Andrew Riordan, MD, FRCPCH, MRCP, DTM&H
Consultant in Paediatric Infectious Diseases and Immunology
Royal Liverpool Children's Hospital (Alder Hey)
Liverpool
UK
Раскрытие информации
AR declares that he has no competing interests.
David Cassarino, MD, PhD
Assistant Professor
Department of Pathology and Laboratory Medicine
University of California
Los Angeles
CA
Раскрытие информации
DC declares that he has no competing interests.
Leonid Izikson, MD
Staff Dermatologist
Department of Dermatology
Massachusetts General Hospital
Boston
MA
Раскрытие информации
LI declares that he has no competing interests.
Aisha Sethi, MD
Assistant Professor of Medicine
Associate Residency Program Director
University of Chicago
Chicago
IL
Раскрытие информации
AS declares that she has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
Alsop J, Flewett TH, Foster JR. "Hand-foot-and-mouth disease" in Birmingham in 1959. Br Med J. 1960;2:1708-1711.Полный текст Аннотация
Ishimaru Y, Nakano S, Yamaoka K, et al. Outbreaks of hand, foot, and mouth disease by enterovirus 71. High incidence of complication disorders of central nervous system. Arch Dis Child. 1980;55:583-588.Полный текст Аннотация
Saguil A, Kane SF, Lauters R, et al. Hand-foot-and-mouth disease: rapid evidence review. Am Fam Physician. 2019 Oct 1;100(7):408-14.Полный текст Аннотация
Chang LY, Tsao KC, Hsia SH, et al. Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan. JAMA. 2004;291:222-227.Полный текст Аннотация
Chang LY, Lin TY, Huang YC, et al. Comparison of enterovirus 71 and coxsackie-virus A16 clinical illnesses during the Taiwan enterovirus epidemic, 1998. Pediatr Infect Dis J. 1999;18:1092-1096. Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Отличия
- Aphthous stomatitis or oral aphthous ulcers
- Herpes simplex
- Herpangina
Больше ОтличияРекомендации
- A guide to clinical management and public health response for hand, foot and mouth disease (HFMD)
Больше Рекомендации
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