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Erythema infectiosum

最后审阅: 20 Aug 2025
最后更新: 15 Nov 2024

小结

定义

病史和体格检查

关键诊断因素

  • close contact with other infected individuals
  • bright red macular erythema of the bilateral cheeks with sparing of the nasal ridge and perioral areas
  • erythematous macules and papules evolving into lacy reticular erythema, most notable on the extremities
  • immunodeficiency
完整详情

其他诊断因素

  • arthralgia/arthritis
  • prodrome (fever, headache, pharyngitis, coryza, abdominal pain)
  • symptoms of anemia
完整详情

危险因素

  • close contact with other infected individuals
  • immunodeficiency
  • age 6 to 10 years
完整详情

诊断性检查

首要检查

  • clinical diagnosis
完整详情

需考虑的检查

  • CBC
  • reticulocyte count
  • serology
  • DNA assays
完整详情

治疗流程

急症处理

fever

secondary arthritis

持续性治疗

persistent (>3 weeks) parvovirus B19 infection

撰稿人

作者

Joseph M. Lam, MD

Clinical Associate Professor, Department of Pediatrics

Associate Member, Department of Dermatology and Skin Sciences

University of British Columbia, BC Children’s Hospital

Vancouver

BC

Canada

利益声明

JML declares that he has no relevant competing interests.

Alexander K. C. Leung, MD

Department of Pediatrics

The University of Calgary, Alberta Children's Hospital

Calgary

Alberta

Canada

利益声明

AKCL declares that he has no relevant competing interests.

鸣谢

Dr Joseph M. Lam and Dr Alexander Leung would like to gratefully acknowledge Dr Kari L. Martin, Dr Christine T. Lauren, Dr Jon Dyer, and Dr Jennifer Holman, the previous contributors to this topic. KLM has served as a board member for Women's Dermatologic Society and American Contact Dermatitis Society. CTL, JD, and JH declare that they have no competing interests.

同行评议者

Nevio Cimolai, MD

Professor

Department of Pathology and Laboratory Medicine

Children's and Women's Health Centre of British Columbia

Vancouver

Canada

Disclosures

NC declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Young NS, Brown KE. Parvovirus B19. N Engl J Med. 2004;350:586-597. Abstract

UK Health Security Agency. Parvovirus B19: guidance, data and analysis. Aug 2024 [internet publication].Full text

Cherry JD. Parvovirus infections in children and adults. Adv Pediatr. 1999;46:245-69. Abstract

Kimberlin DW, Banerjee R, Barnett ED, et al. Red book: 2024-2027 report of the Committee on Infectious Diseases. 33rd ed. Elk Grove Village, IL: American Academy of Pediatrics; 2024.

Centers for Disease Control and prevention. Parvovirus B19 and fifth disease. Nov 2019 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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