Last reviewed: July 2020
Last updated: January  2020

Summary

Definition

History and exam

Key diagnostic factors

  • first-born male infant
  • non-bilious projectile vomiting
  • 3 to 6 weeks old
  • upper abdominal mass
  • peristaltic waves

Other diagnostic factors

  • family history of pyloric stenosis
  • multiple formula changes
  • tachycardia
  • decreased wet nappies
  • dry mucous membranes
  • flat or depressed fontanelles
  • constipation
  • poor weight gain
  • irritability

Risk factors

  • prematurity
  • early exposure to erythromycin
  • maternal exposure to macrolides
  • first-born male infant
  • family history of pyloric stenosis

Diagnostic investigations

Treatment algorithm

Contributors

Assistant Professor of Pediatric Surgery

Ann and Robert H. Lurie Children’s Hospital of Chicago

Chicago

IL

Disclosures

CJH declares that she has no competing interests.

Pediatric Surgery Research Fellow

Ann and Robert H. Lurie Children’s Hospital of Chicago

Chicago

IL

Disclosures

SCK declares that he has no competing interests.

Dr Catherine Hunter would like to gratefully acknowledge Dr Jeffrey S. Upperman, Dr Yigit S. Guner, and Dr Arturo Aranda, previous contributors to this topic. JSU, YSG, and AA declare that they have no competing interests.

Peer reviewersVIEW ALL

Assistant Professor of Surgery

Department of Surgery

Division of Pediatric Surgery

NYU Medical Center

New York

NY

Disclosures

EN declares that he has no competing interests.

Emeritus Nuffield Professor of Paediatric Surgery

Institute of Child Health

University College

London

UK

Disclosures

LS declares that he has no competing interests.

Consultant in Paediatric and Neonatal Surgery

Royal Alexandra Children's Hospital

Brighton

UK

Disclosures

RH declares that she has no competing interests.

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