Summary
Definition
History and exam
Other diagnostic factors
- pelvic pain
- bloating and early satiety
- palpable adnexal mass
Risk factors
- pre-menopausal age group
- early menarche
- first trimester of pregnancy
- personal history of infertility or polycystic ovarian syndrome
- increased intrinsic or extrinsic gonadotrophins
- tamoxifen therapy
- smoking
- personal or family history of endometriosis
Diagnostic investigations
Investigations to consider
- serum cancer antigen (CA)-125
- colour power Doppler ultrasonography of abdomen/pelvis
- MRI of abdomen/pelvis
- CT imaging of abdomen/pelvis
- karyotype analysis
- laparoscopy/laparotomy and histopathology
Emerging tests
- PET imaging of abdomen/pelvis
- serum biomarkers (ovarian adnexal mass assessment score test system)
Treatment algorithm
Contributors
Authors

Professor and Chairman
Department of Obstetrics and Gynecology
Northeast Ohio Medical University
Aultman Health Foundation OB/GYN Residency
Canton
OH
Disclosures
MPH declares that he has no competing interests.
Dr Michael P. Hopkins would like to gratefully acknowledge Dr Christina N. Kufel, Dr Lauren M. Blue, Dr Jay R. Patibandla, and Dr Laura K. Randolph, previous contributors to this topic.
Disclosures
CNK, LMB, JRP, and LKR declare that they have no competing interests.
Peer reviewers
Consultant in Family Medicine
Parker D Sanders and Isabella Sanders Professor of Primary Care
Rochester
MN
Disclosures
JB declares that he has no competing interests.
Chair
Department of Obstetrics and Gynecology
Virginia Commonwealth University
Richmond
VA
Disclosures
DC declares that he has no competing interests.
Consultant Obstetrician and Gynaecologist
Birmingham Women's Hospital
Obstetrics and Gynaecology
Birmingham
UK
Disclosures
TJC declares that he has no competing interests.
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