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Lichen simplex chronicus

Последний просмотренный: 25 Set 2025
Last updated: 27 Mar 2024

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • presence of risk factors
  • underlying dermatosis
  • pruritus beginning during psychological stress
  • severe intractable itching
  • lichenification
  • erythematous to violaceous plaques
  • lesions on neck, ankles, scalp, vulva, scrotum, pubis, and extensor forearms
Полная информация

Другие диагностические факторы

  • altered pigmentation
  • erosions
  • linear fissures
  • grouped hyperpigmented papules on the shins
  • hyperpigmented patch on the interscapular back
  • underlying psychiatric disorder
  • underlying systemic condition causing pruritus
Полная информация

Факторы риска

  • atopic diathesis
  • environmental irritants
  • psychiatric disorder
  • dermatological disease
  • systemic conditions causing pruritus
Полная информация

Диагностические исследования

Исследования, проведение которых нужно рассмотреть

  • skin biopsy
  • patch testing
  • potassium hydroxide preparation
  • fungal culture
  • skin scrapings
  • serum TSH and free T4
  • serum creatinine and urea and electrolytes
  • LFTs and gamma-GT
  • FBC
Полная информация

Алгоритм лечения

ПРОДОЛЖЕНИЕ

adults and children ≥12 years

children <12 years

Составители

Авторы

Brian L. Swick, MD
Brian L. Swick

Clinical Professor

University of Iowa Departments of Dermatology and Pathology

Iowa City Veterans Affairs Medical Center

Iowa City

IA

Раскрытие информации

BLS declares that he has no competing interests.

Рецензенты

Gil Yosipovitch, MD, FAAD

Professor

Stiefel Chair of Medical Dermatology

Director Miami Itch Center

Dr Phillip Frost Department of Dermatology and Cutaneous Surgery

Miller School of Medicine

University of Miami

Miami

FL

Раскрытие информации

GY is an advisory board member for Abbvie, Arcutis, Escient Health, Eli Lilly, Galderma, LEO Pharma, Novartis, Pfizer, Pierre Fabre, Regeneron Pharmaceuticals, Inc., Sanofi, Vifor, GSK, and Kamari. He has received grants/research funding from Eli Lilly, LEO Pharma, Novartis, Pfizer, Galderma, Escient, Sanofi Regeneron, and Celldex. GY is an investigator for Regeneron Pharmaceuticals, Inc., and Sanofi.

Helen Goodyear, MBChB, MRCP, FRCPCH, MD, MMed

Consultant Paediatrician

Heartlands Hospital

Birmingham

UK

Раскрытие информации

HG declares that she has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Lotti T, Buggaiani G, Prignano F. Prurigo nodularis and lichen simplex chronicus. Dermatol Ther. 2008;21:42-46.Полный текст  Аннотация

Primary Care Dermatology Society. Lichen simplex (syn. circumscribed neurodermatitis). Jun 2022 [internet publication].Полный текст

van der Meijden WI, Boffa MJ, Ter Harmsel B, et al. 2021 European guideline for the management of vulval conditions. J Eur Acad Dermatol Venereol. 2022 Jul;36(7):952-72.Полный текст  Аннотация

American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].Полный текст

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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