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Lichen planus

Последний просмотренный: 11 Jun 2025
Last updated: 20 Dec 2024

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • pruritus
  • violaceous, flat-topped papules or plaques
  • Wickham striae
  • mucosal erosions and lacy white network
  • scarring alopecia
  • nail involvement
Полная информация

Другие диагностические факторы

  • dorsal pterygium
  • history of hepatitis C (HCV)
Полная информация

Факторы риска

  • hepatitis C (in some patient populations)
  • -308 G/A polymorphism in TNF-alpha gene
  • hepatitis B vaccination
  • influenza vaccination
  • coronavirus disease 2019 (COVID-19) vaccination
  • psychosocial stress
  • oral allergens
  • use of certain drugs
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • clinical diagnosis
Полная информация

Исследования, проведение которых нужно рассмотреть

  • histopathology
  • hepatitis C screen
  • immunofluorescence
Полная информация

Алгоритм лечения

Острый

cutaneous disease

scalp disease

oral disease

genital disease

nail disease

Составители

Авторы

Deepani Munidasa, MBBS, MD

Consultant Dermatologist

Department of Dermatology

Anuradhapura Teaching Hospital

Anuradhapura

Sri Lanka

Раскрытие информации

DM declares that she has no competing interests.

Выражение благодарностей

Dr Deepani Munidasa would like to gratefully acknowledge Dr Susan Cooper, Dr Rebecca Dunn, Dr Julia S. Lehman, Dr Megha M. Tollefson, and Dr Lawrence E. Gibson, previous contributors to this topic.

Раскрытие информации

SC is chair of the British Society for the Study of Vulval Disease and receives royalties for contributions to UpToDate. RD, JSL, MMT, and LEG declare that they have no competing interests.

Рецензенты

Brian Swick, MD

Clinical Assistant Professor

University of Iowa College of Medicine

Iowa City

IA

Раскрытие информации

BS declares that he has no competing interests.

David Cassarino, MD, PhD

Assistant Professor

Department of Pathology and Laboratory Medicine

University of California

Los Angeles

CA

Раскрытие информации

DC declares that he has no competing interests.

Список литературы

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Основные статьи

American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].Полный текст  Аннотация

Edwards SK, Bates CM, Lewis F, et al. 2014 UK national guideline on the management of vulval conditions. Int J STD AIDS. 2015 Aug;26(9):611-24. Аннотация

Ioannides D, Vakirlis E, Kemeny L, et al. European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):1403-14.Полный текст  Аннотация

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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