小结
定义
病史和体格检查
关键诊断因素
- alcohol use
- change in mental status
- hallucinations
- seizures
- delusions
- hypertension or hypotension
- fever or hypothermia
- hyperglycemia or hypoglycemia
- features of clinical instability
其他诊断因素
- tremor
- nausea and vomiting
- anorexia
- anxiety/restlessness
- emotional lability
- insomnia
- irritability
- diaphoresis
- headache
- fine tremor
- agitation
- tachycardia
危险因素
- history of alcohol withdrawal syndrome (AWS) and alcohol withdrawal delirium
- abrupt withdrawal of alcohol
诊断性检查
首要检查
- BUN and serum creatinine
- LFTs
- ethanol concentration
- electrolyte panel
- CBC
需考虑的检查
- CT of head
- chest x-ray
- electroencephalogram (EEG)
- blood-borne virus screen
治疗流程
all patients
撰稿人
专家顾问
Hong K. Kim, MD, MPH
Associate Professor
Department of Emergency Medicine
University of Maryland School of Medicine
Baltimore
MD
利益声明
HKK declares that he has no competing interests.
Nicholas J. Connors, MD
Program Director
HCA Healthcare/Mercer University/Trident Medical Center
Emergency Medicine Residency Program
Charleston
SC
利益声明
NJC declares that he has no competing interests.
同行评议者
Kinjal Sethuraman, MD, MPH
Associate Director
International Emergency Medicine
Long Island Jewish Hospital
New York
NY
利益声明
KS declares that he has no competing interests.
Paul S. Haber, MD
Royal Prince Alfred Hospital and Discipline of Medicine
The University of Sydney
Sydney
Australia
利益声明
PSH is an author of a reference cited in this topic.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
参考文献
关键文献
Bayard M, McIntyre J, Hill KR, et al. Alcohol withdrawal syndrome. Am Fam Physician. 2004 Mar 15;69(6):1443-50.全文 摘要
American Society of Addiction Medicine. The ASAM clinical practice guideline on alcohol withdrawal management. J Addict Med. 2020 May/Jun;14(3s suppl 1):1-72.全文 摘要
Bråthen G, Ben-Menachem E, Brodtkorb E, et al. Chapter 29: alcohol-related seizures. EFNS guidelines of alcohol-related seizures. In: Gilhus NE, Barnes MP, Brainin M, eds. European handbook of neurological management. 2nd ed, v1. Oxford, UK: Blackwell Publishing; 2011:429-36.
American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed. Text revision. (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.
参考文献
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
鉴别诊断
- Sympathomimetic toxicity
- Encephalitis
- Meningitis
更多 鉴别诊断指南
- The ASAM clinical practice guideline on alcohol withdrawal management
- Assessment and management of alcohol dependence and withdrawal in the acute hospital
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Alcohol Consumption Screening AUDIT Questionnaire
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