Assessment of hyperprolactinaemia

Last reviewed: 7 Jun 2022
Last updated: 22 Apr 2022

Summary

Differentials

Common

  • Prolactinoma
  • Primary hypothyroidism
  • Drug-induced hyperprolactinaemia
  • Macroprolactinaemia
  • Pregnancy
Full details

Uncommon

  • Acromegaly
  • Hypothalamic mass compressing pituitary stalk
  • Multiple endocrine neoplasia syndrome type I (MEN I)
  • Traumatic sectioning of pituitary stalk
  • Lymphocytic hypophysitis
  • Granulomatous hypophysitis
  • Polycystic ovary syndrome
  • Chronic kidney disease
  • Cirrhosis
  • Chest wall trauma or surgery
  • Ectopic hyperprolactinaemia
  • Idiopathic hyperprolactinaemia
Full details

Contributors

Authors

Panagiotis Anagnostis, MD, MSc, PhD, FRSPH

Endocrinologist

Department of Internal Medicine

Medical School

Aristotle University of Thessaloniki

Thessaloniki

Greece

Disclosures

PA declares that he has no competing interests.

Acknowledgements

Dr Panagiotis Anagnostis would like to gratefully acknowledge Professor Faidon Harsoulis, a previous contributor to this topic.

Disclosures

FH declared that he had no competing interests.

Peer reviewers

Subhash Kini, MD, FRCS

Assistant Professor

Mount Sinai Medical Center

New York

NY

Disclosures

SK declares that he has no competing interests.

John C. Marshall, MD, PhD

Professor of Medicine

Director

Center for Research in Reproduction

University of Virginia Health System

Charlottesville

VA

Disclosures

JCM has received NIH funding of over 6 figures USD. JCM declares that he has no competing interests.

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