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Barrett esophagus

Última revisão: 24 Jul 2025
Última atualização: 15 Oct 2024

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • heartburn
  • regurgitation
  • dysphagia
Detalhes completos

Outros fatores diagnósticos

  • incidental finding during gastrointestinal endoscopy for other indication
  • chest pain
  • laryngitis
  • cough
  • dyspnea or wheezing
  • history of aspiration pneumonia
Detalhes completos

Fatores de risco

  • acid/bile reflux or GERD
  • increased age
  • white ethnicity
  • male sex
  • family history of Barrett esophagus or esophageal adenocarcinoma
  • obesity
  • smoking
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • upper GI endoscopy with biopsy
  • barium esophagogram
Detalhes completos

Novos exames

  • chromoendoscopy
  • autofluorescence imaging
  • confocal laser endomicroscopy
  • optical coherence tomography
  • spectroscopy
  • transnasal endoscopy
  • capsule endoscopy
  • gelatin-coated sponge

Algoritmo de tratamento

AGUDA

nondysplastic Barrett esophagus

low-grade dysplasia

high-grade dysplasia

Colaboradores

Autores

Andres F. Carrion, MD

Associate Professor of Medicine

Division of Gastroenterology and Hepatology

University of Miami

Miller School of Medicine

Miami

FL

Declarações

AFC is a scientific advisor for Intercept Pharmaceuticals and Gilead Sciences, and is on the speaker bureau for Bristol-Myers Squibb, Intercept Pharmaceuticals, Merck, and Alexion.

Ricardo Badillo, MD

Assistant Professor of Medicine

Division of Gastroenterology

Texas Tech University Health Sciences Center

El Paso

TX

Declarações

RB declares that he has no competing interests.

Marc J. Zuckerman, MD

Professor of Medicine

Chief

Division of Gastroenterology

Texas Tech University Health Sciences Center

El Paso

TX

Declarações

MJZ is on the speakers bureau for Phathom Pharmaceuticals.

Agradecimentos

Dr Andres F. Carrion, Dr Ricardo Badillo and Dr Marc J. Zuckerman would like to gratefully acknowledge Dr Vic Velanovich, the previous contributor to this topic.

Declarações

VV is an author of a number of references cited in this topic.

Revisores

Richard E. Sampliner, MD

Professor

Medicine Chief

Department of Gastroenterology

University of Arizona College of Medicine

Tucson

AZ

Declarações

RES declares that he has no competing interests.

Peter McCulloch, MBChB, MA, MD, FRCS (Ed), FRCS (Glas)

Clinical Reader in Surgery

Nuffield Department of Surgery

University of Oxford

Oxford

UK

Declarações

PM declares that he has no competing interests.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

Fitzgerald RC, di Pietro M, Ragunath K, et al. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus. Gut. 2014 Jan;63(1):7-42.Texto completo  Resumo

Shaheen NJ, Falk GW, Iyer PG, et al. Diagnosis and management of Barrett's esophagus: an updated ACG guideline. Am J Gastroenterol. 2022 Apr 1;117(4):559-87.Texto completo  Resumo

Fitzgerald RC. Molecular basis of Barrett's oesophagus and oesophageal adenocarcinoma. Gut. 2006 Dec;55(12):1810-20. Resumo

Weusten B, Bisschops R, Coron E, et al. Endoscopic management of Barrett's esophagus: European Society of Gastrointestinal Endoscopy (ESGE) position statement. Endoscopy. 2017 Feb;49(2):191-8.Texto completo  Resumo

Sharma P, Dent J, Armstrong D, et al. The development and validation of an endoscopic grading system for Barrett's esophagus: the Prague C & M criteria. Gastroenterology. 2006 Nov;131(5):1392-9.Texto completo  Resumo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
  • Barrett esophagus images
  • Diagnósticos diferenciais

    • Esophagitis
    • GERD
    • Esophageal adenocarcinoma
    Mais Diagnósticos diferenciais
  • Diretrizes

    • Endoscopic eradication therapy of Barrett’s esophagus and related neoplasia
    • Adverse events associated with EGD and EGD-related techniques
    Mais Diretrizes
  • Folhetos informativos para os pacientes

    Sore throat

    Acid reflux, heartburn, and gastroesophageal reflux disease (GERD)

    Mais Folhetos informativos para os pacientes
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