Summary
Definition
History and exam
Key diagnostic factors
- heartburn
- regurgitation
- dysphagia
Other diagnostic factors
- incidental finding during gastrointestinal endoscopy for other indication
- chest pain
- laryngitis
- cough
- dyspnea or wheezing
- history of aspiration pneumonia
Risk factors
- acid/bile reflux or GERD
- increased age
- white ethnicity
- male sex
- family history of Barrett esophagus or esophageal adenocarcinoma
- obesity
- smoking
Diagnostic investigations
1st investigations to order
- upper GI endoscopy with biopsy
- barium esophagogram
新兴检查
- chromoendoscopy
- autofluorescence imaging
- confocal laser endomicroscopy
- optical coherence tomography
- spectroscopy
- transnasal endoscopy
- capsule endoscopy
- gelatin-coated sponge
治疗流程
nondysplastic Barrett esophagus
low-grade dysplasia
high-grade dysplasia
撰稿人
作者
Andres F. Carrion, MD
Associate Professor of Medicine
Division of Gastroenterology and Hepatology
University of Miami
Miller School of Medicine
Miami
FL
利益声明
AFC is a scientific advisor for Intercept Pharmaceuticals and Gilead Sciences, and is on the speaker bureau for Bristol-Myers Squibb, Intercept Pharmaceuticals, Merck, and Alexion.
Ricardo Badillo, MD
Assistant Professor of Medicine
Division of Gastroenterology
Texas Tech University Health Sciences Center
El Paso
TX
利益声明
RB declares that he has no competing interests.
Marc J. Zuckerman, MD
Professor of Medicine
Chief
Division of Gastroenterology
Texas Tech University Health Sciences Center
El Paso
TX
利益声明
MJZ is on the speakers bureau for Phathom Pharmaceuticals.
鸣谢
Dr Andres F. Carrion, Dr Ricardo Badillo and Dr Marc J. Zuckerman would like to gratefully acknowledge Dr Vic Velanovich, the previous contributor to this topic.
利益声明
VV is an author of a number of references cited in this topic.
同行评议者
Richard E. Sampliner, MD
Professor
Medicine Chief
Department of Gastroenterology
University of Arizona College of Medicine
Tucson
AZ
利益声明
RES declares that he has no competing interests.
Peter McCulloch, MBChB, MA, MD, FRCS (Ed), FRCS (Glas)
Clinical Reader in Surgery
Nuffield Department of Surgery
University of Oxford
Oxford
UK
利益声明
PM declares that he has no competing interests.
鉴别诊断
- Esophagitis
- GERD
- Esophageal adenocarcinoma
更多 鉴别诊断指南
- Endoscopic eradication therapy of Barrett’s esophagus and related neoplasia
- Adverse events associated with EGD and EGD-related techniques
更多 指南患者教育信息
Heartburn
Sore throat
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