When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Anorexia nervosa

Última revisão: 5 Aug 2025
Última atualização: 22 May 2025

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • significantly low body weight
  • fear of gaining weight or becoming fat, or behaviors that interfere with weight gain despite evidence of significantly low body weight
  • disturbed body image
  • calorie restriction
  • binge-eating and/or purging
  • misuse of laxatives, diuretics, or diet pills
  • amenorrhea
  • decreased subcutaneous fat
Detalhes completos

Outros fatores diagnósticos

  • general fatigue, muscle weakness, and poor concentration
  • significant preoccupation with thoughts of food
  • orthostatic hypotension
  • nonspecific gastrointestinal symptoms
  • cardiac symptoms and signs
  • changes to hair, skin, and nails
  • dependent edema
  • osteopenia or osteoporosis
Detalhes completos

Fatores de risco

  • female sex
  • adolescence and puberty
  • obsessive and perfectionist traits
  • exposure to Western media
  • genetic influence
  • middle and upper socioeconomic classes
  • athlete
  • appearance-related teasing
  • childhood maltreatment
  • celiac disease
  • type 1 diabetes mellitus
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • clinical diagnosis
  • CBC
  • serum chemistry
  • thyroid function tests
  • liver function tests
  • blood glucose
  • urinalysis
  • Sit Up-Stand-Squat (SUSS) test
Detalhes completos

Investigações a serem consideradas

  • Sick, Control, One, Fat, and Food (SCOFF) questionnaire
  • ECG
  • bone densitometry (dual-energy x-ray absorptiometry)
  • estradiol in females
  • testosterone in males
  • urine or serum pregnancy test
Detalhes completos

Algoritmo de tratamento

AGUDA

medically stable and suitable for outpatient treatment

medically unstable or outpatient failure

Colaboradores

Autores

Evelyn Attia, MD

Professor of Psychiatry

Columbia University and Weill Cornell Medical College

New York

NY

Declarações

EA receives royalties from UpToDate and Oxford University Press for authorship and has served as a clinical advisor to Equip Health, Inc.

B. Timothy Walsh, MD

Professor of Psychiatry

Columbia University

New York

NY

Declarações

BTW has received royalties and honoraria for writing, editing, speaking, or consulting from Guilford Publications, McGraw-Hill, Oxford University Press, UpToDate, Wiley, the University of British Columbia, Silverhill Hospital, the University of Alabama, the American Society for Clinical Psychopharmacology, Health Advances, and Dell Medical School.

Agradecimentos

Professor Evelyn Attia and Professor B. Timothy Walsh would like to gratefully acknowledge Dr Pauline S. Powers and Dr Abby M. Irwin, previous contributors to this topic.

Declarações

PSP and AMI declare that they have no competing interests.

Revisores

Heather Thompson-Brenner, MD

Director

Eating Disorders Program Center for Anxiety and Related Disorders

Psychology Department

Boston University

Boston

MA

Declarações

HTB declares that she has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.

National Institute for Health and Care Excellence. Eating disorders: recognition and treatment. Dec 2020 [internet publication].Texto completo

American Psychiatric Association. Practice guideline for the treatment of patients with eating disorders. Feb 2023 [internet publication].Texto completo

Royal College of Psychiatrists. Medical emergencies in eating disorders (MEED): guidance on recognition and management. Oct 2023 [internet publication].Texto completo

Hornberger LL, Lane MA, Committee on Adolescence. Identification and management of eating disorders in children and adolescents. Pediatrics. 2021 Jan;147(1):e2020040279.Texto completo  Resumo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
  • Anorexia nervosa images
  • Diagnósticos diferenciais

    • Bulimia nervosa
    • Avoidant-restrictive food intake disorder (ARFID)
    • Depression
    Mais Diagnósticos diferenciais
  • Diretrizes

    • Determining treatment goal weights for children and adolescents with anorexia nervosa
    • World Federation of Societies of Biological Psychiatry (WFSBP) guidelines update 2023 on the pharmacological treatment of eating disorders
    Mais Diretrizes
  • Folhetos informativos para os pacientes

    Anorexia

    Anorexia: questions to ask your doctor

    Mais Folhetos informativos para os pacientes
  • Calculadoras

    Body Mass Index (BMI) percentiles for boys (2 to 20 years)

    Body Mass Index (BMI) percentiles for girls (2 to 20 years)

    Mais Calculadoras
  • padlock-lockedConectar-se ou assinar para acessar todo o BMJ Best Practice

O uso deste conteúdo está sujeito ao nosso aviso legal