Hearing loss is one of the most common sensory impairments. It affects people of all ages and can be permanent if not treated correctly. Proper diagnosis rests on a thorough understanding of ear anatomy and physiology.
The human ear is divided into 3 parts: the external ear, the middle ear, and the inner ear.
The external ear consists of the auricle (or pinna), the ear canal, and the tympanic membrane (or ear drum). The tympanic membrane divides the external ear from the middle ear.
Like the external ear, in its normal state, the middle ear is filled with air. Connected to the malleus (or hammer) is the incus (anvil), which is then connected to the stapes (stirrup). On the medial wall of the middle ear is the promontory, which demarcates the inner ear and, specifically, the basal turn of the cochlea. The stapes sits in an area called the oval window. The round window is inferior to the oval window. These windows lead to the inner ear.
The inner ear is fluid-filled and contains the organs of hearing (the cochlea) and the organs of balance (the semicircular canals, utricle, and saccule). The cochleovestibular nerve connects the end organs to the auditory and vestibular pathways.
Sound waves require a medium, such as air or water. The compression in a sound wave is channelled down the ear canal to the tympanic membrane. Vibrations of the tympanic membrane are then transmitted by the ossicular chain through the oval window into the cochlea. The vibrations of the cochlea cause a fluid wave, which stimulates hair cells within the cochlea, generating an electrical impulse, which is transmitted along the cochlear nerve to the brain, where it is heard/interpreted. Mechanical energy is thereby converted to electrical energy. Anything that interferes with the movement of sound from the external ear to the middle ear to the inner ear, and then to the brain, can cause a hearing loss. The external ear and middle ear may appear normal on examination if the cause is in the inner ear or brain. It is possible for hearing loss to be permanent if not treated in a timely fashion.
Generally, hearing loss is classified as conductive or sensorineural.
Conductive hearing loss occurs usually in the external and middle ear by interfering with the ability of sound to be transmitted to the inner ear. Many causes can be treated successfully with surgery.
Sensorineural hearing losses occur in the inner ear (sensory) or auditory nerve/auditory pathway (neural). Many sensorineural hearing losses are permanent because the human inner ear and hair cells have only limited ability to repair themselves, unlike avian hair cells, which can re-generate after trauma or injury. 
Department of Otolaryngology
Virginia Mason Medical Center
The Listen for Life Center at Virginia Mason
SRS is an author of a reference cited in this topic.
Dr S.R. Schwartz would like to gratefully acknowledge Dr S.J. Marzo, Dr J.P. Leonetti, and Dr R.J. Buckingham, previous contributors to this topic. SJM, JPL, and RJB declare that they have no competing interests.
Department of Otolaryngology
Department of Neurosurgery
Northwestern University Feinberg School of Medicine
AM declares that he has no competing interests.
Professor of Otorhinolaryngology
MRC Institute of Hearing Research
GB is an author of several books that include discussion of evaluation of hearing loss.
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