When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Long bone fracture

Evidence last reviewed: 29 Mar 2026
Topic last updated: 24 Feb 2026

Summary

Definition

History and exam

Key diagnostic factors

  • pain
  • soft tissue swelling
  • ecchymosis
  • expanding hematoma
  • impaired limb function
  • inability to bear weight
  • point tenderness
  • deformity
  • guarding
  • wound overlying or near site of injury
  • signs of vascular injury
  • signs of acute compartment syndrome
  • hypotension/hypovolemic shock
Full details

Other diagnostic factors

  • altered nerve sensation
  • impaired motor function
  • bony crepitus
  • callus
  • reproduction of symptoms in stress fractures of the neck or shaft of the femur
Full details

Risk factors

  • direct trauma
  • indirect trauma
  • osteoporosis (insufficiency fractures)
  • chronic renal failure
  • bone tumor (pathologic fractures)
  • age >70 years
  • age <30 years
  • diabetes mellitus
  • male sex (acute fractures)
  • female sex (fatigue and insufficiency fractures)
  • prolonged corticosteroid use (insufficiency fractures)
  • low BMI (insufficiency fractures)
  • history of recent fall (insufficiency fractures)
  • prior fracture (insufficiency fractures)
  • seizures (proximal humerus fracture)
  • long-term bisphosphonate use
  • smoking
  • alcohol
Full details

Diagnostic investigations

1st investigations to order

  • x-ray limb
  • CBC, blood typing, and cross-matching (major trauma)
  • lactate
  • base excess
Full details

Investigations to consider

  • MRI of area of interest without IV contrast
  • noncontrast CT of fracture
  • whole body bone scan with SPECT or SPECT/CT area of interest
  • compartment pressure testing
  • Doppler pressure (ankle/brachial systolic pressure index)
  • ultrasound duplex scanning
  • CT angiogram
  • angiography
  • dual-energy x-ray absorptiometry bone density scan
  • whole-body CT
Full details

Treatment algorithm

INITIAL

involved in high-energy trauma

ACUTE

distal humeral shaft: nonstress

midshaft humeral: nonstress

proximal humeral shaft: nonstress

radial or ulnar shaft: nonstress

upper limb stress fractures

femoral shaft: nonstress

tibia or fibula shaft: nonstress

femoral stress fractures

fibular or tibial stress fractures

კონტრიბუტორები

ავტორები

Nathan Olszewski, MD

Assistant Professor of Orthopedic Surgery

Orthopedic Surgeon

Boston University Chobanian & Avedisian School of Medicine

Boston Medical Center

Department of Orthopaedic Surgery

Boston

MA

გაფრთხილება:

NO has been reimbursed for travel from Stryker Corporation for participation in educational case conferences and equipment training sessions.

Paul Tornetta, III, MD, PhD

Chief and Chair, Professor and Residency Program Director, Director of Orthopedic Trauma

Boston University Chobanian & Avedisian School of Medicine

Boston Medical Center

Department of Orthopaedic Surgery

Boston

MA

გაფრთხილება:

PT holds intellectual property with Smith & Nephew and has received publishing royalties from Wolters Kluwer.

მადლიერება

Dr Nathan Olszewski and Dr Paul Tornetta III would like to gratefully acknowledge Dr Philip H. Cohen, the previous contributor to this topic.

Disclosures

PHC has given lectures for MCE Conferences, a medical education company, and received a stipend/free hotel room during the conference. MCE Conferences accepts no funding from pharmaceutical companies or other outside agencies, and PHC declares that the lectures have no impact on the topic.

Revisores

Robert D. Golden, MD

Chief, Orthopaedic Surgery

MedStar Washington Hospital Center

Regional Chief

Orthopaedic Trauma Surgery

MedStar Orthopaedic Institute

Washington

DC

Declarações

RDG declares that he has no competing interests.

Créditos aos pareceristas

Os tópicos do BMJ Best Practice são constantemente atualizados, seguindo os desenvolvimentos das evidências e das diretrizes. Os pareceristas aqui listados revisaram o conteúdo pelo menos uma vez durante a história do tópico.

Declarações

As afiliações e declarações dos pareceristas referem--se ao momento da revisão.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

American College of Radiology. ACR appropriateness criteria: stress (fatigue-insufficiency) fracture including sacrum excluding other vertebrae. 2024 [internet publication].Texto completo

National Institute for Health and Care Excellence. Fractures (complex): assessment and management. Nov 2022 [internet publication].Texto completo

American Academy of Orthopaedic Surgeons. Prevention of surgical site infections after major extremity trauma. Evidence-based clinical practice guideline. Mar 2022 [internet publication].Texto completo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
  • Long bone fracture images
  • Diagnósticos diferenciais

    • Contusion
    • Anterior glenohumeral dislocation
    • Rotator cuff injury
    Mais Diagnósticos diferenciais
  • Diretrizes

    • ACR appropriateness criteria: stress (fatigue-insufficiency) fracture including sacrum excluding other vertebrae
    • Fractures (complex): assessment and management
    Mais Diretrizes
  • padlock-lockedConectar-se ou assinar para acessar todo o BMJ Best Practice

O uso deste conteúdo está sujeito ao nosso aviso legal