Evaluation of fever of unknown origin in adults
Summary
Differentials
Common
- Tuberculosis (TB)
- Abdominal or pelvic abscess
- HIV
- Rhinosinusitis, acute or chronic
- Bacterial pneumonia
- Urinary tract infection
Uncommon
- Infective endocarditis
- Dental abscesses
- Osteomyelitis
- Prostatitis, acute or chronic
- Cytomegalovirus infection
- Epstein-Barr virus infection
- Coronavirus disease 2019 (COVID-19)
- Rheumatic fever
- Lyme disease
- Chronic myeloid leukemia
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Metastatic carcinoma, primary unknown
- Renal cancer
- Myelodysplastic syndrome
- Adult-onset Still disease
- Polymyalgia rheumatica
- Giant cell arteritis
- Systemic lupus erythematosus
- Crohn disease
- Ulcerative colitis
- Rheumatoid arthritis
- Reactive arthritis
- Drug-induced fever
- Cirrhosis, complicated
- Hepatitis
- Deep vein thrombosis
- Sarcoidosis
- Periodic fever syndromes
- Malaria
- Typhoid fever
- Rocky Mountain spotted fever
- Ascariasis
- Tularemia
- Brucellosis
- Psittacosis
- Q fever
- Pheochromocytoma
- Hyperthyroidism
- Munchausen syndrome
- Dengue fever
Contributors
Authors
William F. Wright, DO, MPH
Assistant Professor
Division of Infectious Diseases, Department of Medicine
Johns Hopkins University School of Medicine
Baltimore
MD
Disclosures
WFW declares that he has no competing interests. WFW is an author of references cited in this topic.
Paul G. Auwaerter,, MD
Professor
Division of Infectious Diseases, Department of Medicine
The Sherrilyn and Ken Fisher Center for Environmental Infectious Diseases
Johns Hopkins University School of Medicine
Baltimore
MD
Disclosures
PGA declares that he has no competing interests. PGA is an author of references cited in this topic.
Acknowledgements
Dr William F. Wright and Dr Paul G. Auwaerter would like to gratefully acknowledge Dr Roth and Dr Basello, previous contributors to this topic.
Рецензенты
Kevin P. High, MD, MS, MACP, FIDSA
Professor of Medicine
Wake Forest University School of Medicine
Vice Chief Academic Officer, aLHS, Advocate Health
Winston-Salem
NC
Раскрытие информации
KPH declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referencias
Artículos principales
Haidar G, Singh N. Fever of unknown origin. N Engl J Med. 2022 Feb 3;386(5):463-77. Resumen
Cunha BA, Lortholary O, Cunha CB. Fever of unknown origin: a clinical approach. Am J Med. 2015 Oct;128(10):1138.e1-1138.e15.Texto completo Resumen
Wright WF, Auwaerter PG. Fever and fever of unknown origin: review, recent advances, and lingering dogma. Open Forum Infect Dis. 2020 May;7(5):ofaa132.Texto completo Resumen
Artículos de referencia
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