Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- history of rheumatic fever
- dyspnoea
- orthopnoea
- opening snap on auscultation
- diastolic murmur
- loud P2
- neck vein distension
- paroxysmal nocturnal dyspnoea
- haemoptysis
- hoarseness
- peripheral oedema
- ascites
Other diagnostic factors
- 40-50 years old in rheumatic mitral stenosis, 70-90 years old in mitral annular calcification (MAC)-related disease
- loud first heart sound (S1)
- irregularly irregular pulse
- flushed cheeks
Risk factors
- streptococcal infection
- female sex
- ergot medications
- serotonergic medications
- systemic lupus erythematosus (SLE)
- amyloidosis
- bronchial carcinoid syndrome
- atherosclerotic risk factors
Diagnostic tests
1st tests to order
- ECG
- CXR
- trans-thoracic echocardiography
Tests to consider
- trans-oesophageal echocardiography (TEE)
- cardiac catheterisation
- dynamic exercise testing
Treatment algorithm
non-pregnant
pregnant
Contributors
Authors
Blase Carabello, MD
Professor Emeritus, East Carolina University
Director Valve Program, Roper St Francis Health Care
Charleston
SC
Disclosures
BC declares that he has no competing interests.
Peer reviewers
John R. Charpie, MD, PhD
Associate Professor of Pediatrics
Medical Director
Pediatric Cardiothoracic Intensive Care Unit
University of Michigan Congenital Heart Center
C.S. Mott Children's Hospital
Ann Arbor
MI
Disclosures
JRC declares that he has no competing interests.
David Leaf, MD, MPH
Professor of Medicine
VA Greater Los Angeles Healthcare System
UCLA School of Medicine
Los Angeles
CA
Divulgaciones
DL declares that he has no competing interests.
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Divulgaciones
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Referencias
Artículos principales
Stollerman GH. Rheumatogenic streptococci and autoimmunity. Clin Immunol Immunopathol. 1991 Nov;61(2 Pt 1):131-42. Resumen
Fawzy ME, Choi WB, Mimish L, et al. Immediate and long-term effect of mitral balloon valvotomy on left ventricular volume and systolic function in severe mitral stenosis. Am Heart J. 1996 Aug;132(2 Pt 1):356-60. Resumen
Writing Committee Members; Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2021 Feb 2;77(4):e25-197.Texto completo Resumen
Wilkins GT, Weyman AE, Abascal VM, et al. Percutaneous balloon dilatation of the mitral valve: an analysis of echocardiographic variables related to outcome and the mechanism of dilation. Br Heart J. 1988 Oct;60(4):299-308.Texto completo Resumen
Palacios IF, Sanchez PL, Harrell LC, et al. Which patients benefit from percutaneous mitral balloon valvuloplasty? prevalvuloplasty and postvalvuloplasty variables that predict long-term outcome. Circulation. 2002 Mar 26;105(12):1465-71.Texto completo Resumen
Reyes VP, Raju Bs, Wynne J, et al. Percutaneous balloon valvuloplasty compared with open surgical commissurotomy for mitral stenosis. N Engl J Med. 1994 Oct 13;331(15):961-7.Texto completo Resumen
Subbarao KS, Nachiappan M, Irineu AP. Transventricular mitral commissurotomy in critical mitral stenosis during pregnancy. Asian Cardiovasc Thorac Ann. 2004 Sep;12(3):233-5. Resumen
Delgado V, Ajmone Marsan N, de Waha S, et al. 2023 ESC guidelines for the management of endocarditis: developed by the task force on the management of endocarditis of the European Society of Cardiology (ESC) endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Nuclear Medicine (EANM). Eur Heart J. 2023 Oct 14;44(39):3948-4042.Texto completo
Artículos de referencia
Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
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