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Mitral stenosis

Last reviewed: 21 Oct 2024
Last updated: 01 Oct 2024

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • history of rheumatic fever
  • dyspnoea
  • orthopnoea
  • opening snap on auscultation
  • diastolic murmur
  • loud P2
  • neck vein distension
  • paroxysmal nocturnal dyspnoea
  • haemoptysis
  • hoarseness
  • peripheral oedema
  • ascites
Full details

Other diagnostic factors

  • 40-50 years old in rheumatic mitral stenosis, 70-90 years old in mitral annular calcification (MAC)-related disease
  • loud first heart sound (S1)
  • irregularly irregular pulse
  • flushed cheeks
Full details

Risk factors

  • streptococcal infection
  • female sex
  • ergot medications
  • serotonergic medications
  • systemic lupus erythematosus (SLE)
  • amyloidosis
  • bronchial carcinoid syndrome
  • atherosclerotic risk factors
Full details

Diagnostic investigations

1st investigations to order

  • ECG
  • CXR
  • trans-thoracic echocardiography
Full details

Investigations to consider

  • trans-oesophageal echocardiography (TEE)
  • cardiac catheterisation
  • dynamic exercise testing
Full details

Treatment algorithm

ONGOING

non-pregnant

pregnant

Contributors

Authors

Blase Carabello, MD
Blase Carabello

Professor Emeritus, East Carolina University

Director Valve Program, Roper St Francis Health Care

Charleston

SC

Disclosures

BC declares that he has no competing interests.

Peer reviewers

John R. Charpie, MD, PhD

Associate Professor of Pediatrics

Medical Director

Pediatric Cardiothoracic Intensive Care Unit

University of Michigan Congenital Heart Center

C.S. Mott Children's Hospital

Ann Arbor

MI

Disclosures

JRC declares that he has no competing interests.

David Leaf, MD, MPH

Professor of Medicine

VA Greater Los Angeles Healthcare System

UCLA School of Medicine

Los Angeles

CA

Disclosures

DL declares that he has no competing interests.

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  • Guidelines

    • 2021 ESC/EACTS guidelines for the management of valvular heart disease
    • 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR guideline for the evaluation and diagnosis of chest pain: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines
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