Mitral valve prolapse

Last reviewed: 21 Apr 2022
Last updated: 08 Feb 2022

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • mid-systolic click
  • late-systolic murmur
More key diagnostic factors

Other diagnostic factors

  • palpitations
Other diagnostic factors

Risk factors

  • family history
  • slim body type
  • connective tissue disorders
  • mitral annular disjunction (MAD)
More risk factors

Diagnostic investigations

1st investigations to order

  • echocardiogram
More 1st investigations to order

Investigations to consider

  • Holter or event monitor
  • cardiac MRI
More investigations to consider

Treatment algorithm

ACUTE

asymptomatic

symptomatic

Contributors

Authors

Brian Griffin, MD

Section Head

Section of Cardiovascular Imaging

Heart and Vascular Institute

Cleveland Clinic

Cleveland

OH

Disclosures

BG declares that he has no competing interests.

Saberio Lo Presti, MD

Advanced Cardiac Imaging Fellow

Heart and Vascular Institute

Cleveland Clinic

Cleveland

OH

Disclosures

SLP declares that he has no competing interests.

Acknowledgements

Dr Brian Griffin and Dr Saberio Lo Presti would like to gratefully acknowledge Dr Carmel Halley and Dr Serge Harb, previous contributors to this topic.

Disclosures

CH and SH declared that they had no competing interests.

Peer reviewers

John Dent, MD

Associate Professor of Internal Medicine

Director of Stress Testing Laboratory and Echocardiography

University of Virginia Health System

Cardiovascular Fellowship Program

Charlottesville

VA

Disclosures

JD declares that he has no competing interests.

Prakash Punjabi, MBBS

Honorary Clinical Senior Lecturer

National Heart and Lung Institute

Imperial College London

London

UK

Disclosures

PP declares that he has no competing interests.

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