Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- left lower quadrant abdominal pain
- leukocytosis
- fever
- rectal bleeding
Other diagnostic factors
- guarding in left lower quadrant
- tenderness in left lower quadrant
- bloating
- constipation
- pelvic tenderness on digital rectal examination
- diffuse abdominal tenderness
- diarrhoea
- palpable abdominal mass
Risk factors
- age >50 years
- low dietary fibre
- diet rich in salt, meat, and sugar
- obesity (BMI >30)
- tobacco smoking
- non-steroidal anti-inflammatory drug and opioid use
Diagnostic investigations
1st investigations to order
- FBC with differential
- urea and electrolytes
- C-reactive protein
Investigations to consider
- contrast CT scan of abdomen
- non-contrast CT scan of abdomen
- abdominal ultrasound (graded-compression)
- MRI
- chest x-ray
- colonoscopy
- sigmoidoscopy
- CT angiogram
- isotope-labelled red blood cell nuclear scan
- diagnostic laparoscopy
- blood culture
- ABG and serum lactate
Treatment algorithm
asymptomatic diverticulosis
symptomatic diverticular disease
acute diverticulitis (uncomplicated)
acute diverticulitis (complicated)
recurrent diverticulitis
Contributors
Expert advisers
Mohamed A. Thaha, PhD, FRCS (Gen Surg), PG Cert Hlt Econ
Senior Lecturer & Consultant in Colorectal Surgery
National Bowel Research Centre
Blizard Institute
Barts and The London School of Medicine and Dentistry
The Royal London Hospital
Queen Mary, University of London
London
UK
Disclosures
MAT declares that he has no competing interests.
Jayan Dewanta Jayasinghe, MD
Locum Consultant in General & Colorectal Surgery
The Royal London Hospital
Barts Health NHS Trust
London
UK
Disclosures
JDJ declares that he has no competing interests.
Acknowledgements
BMJ Best Practice would like to gratefully acknowledge the previous team of expert contributors, whose work has been retained in parts of the content.
Peer reviewers
John Abercrombie, FRCS
General and Colorectal Surgeon
Queen’s Medical Centre
Nottingham
UK
Biography
JA is a former Clinical Lead for General Surgery, Getting It Right First Time.
Disclosures
JA is a council member of the Royal College of Surgeons of England.
Editors
Emma Quigley
Section Editor, BMJ Best Practice
Disclosures
EQ declares that she has no competing interests.
Rachel Wheeler
Lead Section Editor, BMJ Best Practice
Disclosures
RW declares that she has no competing interests.
Julie Costello
Comorbidities Editor, BMJ Best Practice
Disclosures
JC declares that she has no competing interests.
Adam Mitchell
Drug Editor, BMJ Best Practice
Disclosures
AM declares that he has no competing interests.
Differentials
- Endometriosis
- Colorectal cancer
- Appendicitis
More DifferentialsGuidelines
- 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting
- Diverticular disease: diagnosis and management
More GuidelinesPatient information
Appendicitis
Constipation
More Patient information- Log in or subscribe to access all of BMJ Best Practice
Use of this content is subject to our disclaimer