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Cardiac arrest

Last reviewed: 24 Sep 2025
Last updated: 23 Apr 2025

Summary

Definition

History and exam

Key diagnostic factors

  • patient unresponsive
  • absence of normal breathing
  • absence of circulation
  • cardiac rhythm disturbance
Full details

Risk factors

  • coronary artery disease (CAD)
  • left ventricular dysfunction
  • age
  • hypertrophic cardiomyopathy (HCM)
  • arrhythmogenic right ventricular dysplasia (ARVD)
  • long QT syndrome (LQTS)
  • medications that prolong the QT interval or cause electrolyte disturbances
  • acute medical or surgical emergency
  • poisoning
  • Brugada syndrome
  • valvular heart disease
  • smoking
  • history of eating disorders
Full details

Diagnostic tests

1st tests to order

  • continuous cardiac monitoring
  • CBC
  • serum electrolytes
  • ABG
  • cardiac biomarkers
  • point of care ultrasound (POCUS)
Full details

Tests to consider

  • ECG
  • coronary angiography
  • echocardiogram
  • exercise stress testing
  • chest x-ray
  • toxicology screen
  • cardiac magnetic resonance imaging
  • coronary computed tomography angiography
  • signal-averaged ECG (SAECG)
  • electrophysiologic study
Full details

Treatment algorithm

INITIAL

unwitnessed cardiac arrest

ACUTE

shockable rhythms (pulseless ventricular tachycardia or ventricular fibrillation)

nonshockable rhythms (pulseless electrical activity or asystole)

ONGOING

return of spontaneous circulation

no return of spontaneous circulation

Contributors

Авторы

John Wink, MD

Emergency Physician

Alberta Health Services

Alberta

Canada

Раскрытие информации

JW declares that he has no competing interests.

Eddy Lang, MD

Professor and Department Head of Emergency Medicine

Cumming School of Medicine

University of Calgary

Alberta Health Services

Calgary

Canada

Раскрытие информации

EL declares that he has no competing interests.

Выражение благодарностей

Dr John Wink and Professor Eddy Lang would like to gratefully acknowledge Dr Amar Krishnaswamy and Dr Arman T. Askari, previous contributors to this topic.

Раскрытие информации

AK and ATA declare that they have no competing interests.

Рецензенты

Vaikom Mahadevan, MD

Professor of Medicine

Division of Cardiology

University of California

San Francisco

CA

Раскрытие информации

VM declares that he has no competing interests.

Anthony Aizer, MD, MS

Instructor

NYU Department of Medicine (Cardiology)

Leon H Charney Heart Rhythm Center and New York University

New York

NY

Раскрытие информации

AA declares that he has no competing interests.

Massimo F. Piepoli, MD, PhD, FESC

Honorary Clinical Senior Lecturer/Consultant

Department of Cardiology

Imperial College London

London

UK

Раскрытие информации

MFP declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

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Основные статьи

Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: adult basic and advanced life support: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020 Oct 20;142(16_suppl_2):S366-468.Полный текст  Аннотация

Martin SS, Aday AW, Almarzooq ZI, et al. 2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association. Circulation. 2024 Feb 20;149(8):e347-913.Полный текст  Аннотация

Zeppenfeld K, Tfelt-Hansen J, de Riva M, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022 Oct 21;43(40):3997-4126.Полный текст  Аннотация

Al-Khatib SM, Stevenson WG, Ackerman MJ, et al. 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Circulation. 2018 Sep 25;138(13):e272-391.Полный текст  Аннотация

Greif R, Bray JE, Djärv T, et al. 2024 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations: summary from the basic life support; advanced life support; pediatric life support; neonatal life support; education, implementation, and teams; and first aid task forces. Resuscitation. 2024 Dec;205:110414.Полный текст  Аннотация

Nolan JP, Sandroni C, Böttiger BW, et al. European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2021: post-resuscitation care. Intensive Care Med. 2021 Apr;47(4):369-421.Полный текст  Аннотация

Статьи, указанные как источники

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