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Bronchiolitis

最后审阅: 20 Aug 2025
最后更新: 12 Aug 2025

小结

定义

病史和体格检查

关键诊断因素

  • cough
  • tachypnea
  • wheezing
  • retractions, grunting, and nasal flaring
完整详情

其他诊断因素

  • rhinitis
  • fluctuating clinical findings
  • irritability, malaise, and poor feeding
  • fever <104°F (<40°C)
  • crackles
  • apnea
  • thoracoabdominal asynchrony
完整详情

危险因素

  • children <2 years
  • winter months
  • prematurity or bronchopulmonary dysplasia
  • passive tobacco smoke exposure and air pollution
  • impaired airway clearance and function
  • congenital heart disease
  • immunodeficiency
完整详情

诊断性检查

首要检查

  • pulse oximetry
完整详情

Tests to avoid

  • broad respiratory pathogen panels
完整详情

需考虑的检查

  • enzyme-linked immunosorbent assay (ELISA) rapid antigen detection
  • chest x-ray
  • reverse transcriptase polymerase chain reaction (RT-PCR)
完整详情

治疗流程

急症处理

confirmed bronchiolitis

撰稿人

作者

Howard B. Panitch, MD

Emeritus Professor

Division of Pulmonary and Sleep Medicine

Children's Hospital of Philadelphia

Philadelphia

PA

利益声明

HBP is a member of the American Thoracic Society's Guideline Committee, Long-Term Oxygen Therapy for Infants and Children, past Chair of the American College of Chest Physicians' Home Based Mechanical Ventilation and Neuromuscular Disease NetWork, a member of the ATS guideline committee on bronchopulmonary dysplasia (BPD), and a member of the current new guideline committee updating the BPD Statement. He is a member of the planning committee of the Pediatric Assembly of the American Thoracic Society, and receives royalties from Up-To-Date for the review of two topics (Spirometry in Children and Bronchopulmonary Dysplasia).

鸣谢

Professor Panitch would like to gratefully acknowledge Dr Isaac Desheng Liu, Dr Woon Li Seo, Dr Jennifer L. Nayak, Dr Caroline B. Hall, and Dr Clement L. Ren, previous contributors to this topic.

利益声明

IDL, WLS, JLN, and CLR declare that they have no competing interests. CBH is an author of a number of references cited in this topic.

同行评议者

Michael D. Patrick, Jr. MD

Associate Professor of Pediatrics

The Ohio State University College of Medicine

Columbus

OH

利益声明

MDP declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

American Academy of Pediatrics Publications. AAP recommendations for the prevention of RSV disease in infants and children​. Jul 2025 [internet publication].全文

Canadian Paediatric Society. Bronchiolitis: recommendations for diagnosis, monitoring and management of children one to 24 months of age. Nov 2021 [internet publication].全文

Cunningham S, Rodriguez A, Adams T, et al. Oxygen saturation targets in infants with bronchiolitis (BIDS): a double-blind, randomised, equivalence trial. Lancet. 2015 Sep 12;386(9998):1041-8.全文  摘要

Lin J, Zhang Y, Xiong L, et al. High-flow nasal cannula therapy for children with bronchiolitis: a systematic review and meta-analysis. Arch Dis Child. 2019 Jun;104(6):564-76. 摘要

Farley R, Spurling GK, Eriksson L, et al. Antibiotics for bronchiolitis in children under two years of age. Cochrane Database Syst Rev. 2014 Oct 9;(10):CD005189.全文  摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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