Last reviewed: September 2018
Last updated: July  2018

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • localised pain in a dermatome
  • pruritus
  • rash
  • corneal ulceration

Other diagnostic factors

  • fever
  • headache
  • malaise
  • fatigue
  • pain without rash

Risk factors

  • >50 years of age
  • HIV
  • chronic corticosteroid use
  • chemotherapy
  • malignancies
  • white ethnicity

Diagnostic investigations

Investigations to consider

  • polymerase chain reaction (PCR)
  • immunohistochemistry
  • vesicular fluid culture
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Assistant Professor

Center for Value-Based Care Research

Medicine Institute

Cleveland Clinic

Cleveland

OH

Disclosures

PL declares that she has no competing interests.

Professor

Center for Value-Based Care Research

Medicine Institute

Cleveland Clinic

Cleveland

OH

Disclosures

MR declares that he has no competing interests.

Dr Phuc Le and Dr Michael Rothberg would like to gratefully acknowledge Dr Kenneth J. Smith and Dr Linda Kalilani, the previous contributors to this topic. KJS and LK declare that they have no competing interests.

Peer reviewers VIEW ALL

Department of Epidemiology

Division of General Medicine and Epidemiology

UNC at Chapel Hill

Chapel Hill

NC

Disclosures

JA declares that he has no competing interests.

Consultant Virologist

Manchester Royal Infirmary

Manchester

UK

Disclosures

KM declares that he has no competing interests.

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