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Lyme disease

Последний просмотренный: 18 Jun 2025
Last updated: 07 Feb 2025

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • erythema migrans
  • constitutional symptoms
Полная информация

Другие диагностические факторы

  • facial palsy
  • arthritis or arthralgia
  • regional lymphadenopathy
  • stiff neck
  • lymphocytoma cutis
  • acrodermatitis chronica atrophicans
  • atrioventricular (AV) block or myopericarditis
  • radiculoneuropathy
  • encephalomyelitis, peripheral neuropathy, encephalopathy
Полная информация

Факторы риска

  • exposure to infected ticks
  • outdoor activities
  • tick bite duration
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • enzyme immunoassay or immunofluorescence assay
Полная информация

Исследования, проведение которых нужно рассмотреть

  • Lyme-specific IgM and IgG (immunoblot assays)
  • skin biopsy culture
  • polymerase chain reaction (PCR)
  • ECG
Полная информация

Алгоритм лечения

Начальные

known high risk tick bite

Острый

erythema migrans

cardiac involvement

neurologic disease

arthritis

ПРОДОЛЖЕНИЕ

recurrent or persistent arthritis

Составители

Авторы

Janak Koirala, MD, MPH, FACP, FIDSA
Janak Koirala

Professor of Medicine and Infectious Diseases

Division of Infectious Diseases

Southern Illinois University School of Medicine

Springfield

IL

Раскрытие информации

JK declares that he has no competing interests.

Выражение благодарностей

Dr Janak Koirala would like to gratefully acknowledge Dr Tin Han Htwe and Dr Cristian A. Spiel, previous contributors to this topic.

Раскрытие информации

THH and CAS declare that they have no competing interests.

Рецензенты

Raymond J. Dattwyler, MD

Professor of Medicine and Microbiology/Immunology

Chief of Allergy, Immunology and Rheumatology

New York Medical College

Valhalla

NY

Раскрытие информации

RJD declares that he has no competing interests.

Ionita Catalina, MD

Assistant Professor of Neurology and Neurosurgery

SUNY at Buffalo

Stroke/Neurocritical Care

Millard Fillmore Gates Hospital - Kaleida Stroke Center

Buffalo

NY

Раскрытие информации

IC declares that she has no competing interests.

Graham Fry, MB, FRCSI, DTM&H

Lecturer in Tropical Medicine

University College Dublin

Medical Director

Tropical Medical Bureau

Ireland

Раскрытие информации

GF declares that he has no competing interests.

Andras Lakos, MD, PhD

Physician

Centre for Tick-Borne Diseases

Budapest

Hungary

Раскрытие информации

AL is an author of a reference cited in this topic.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Lantos PM, Rumbaugh J, Bockenstedt LK, et al. Clinical practice guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 guidelines for the prevention, diagnosis and treatment of Lyme disease. Clin Infect Dis. 2021 Jan 23;72(1):e1-48.Полный текст  Аннотация

Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 5: travel-associated infections & diseases - Lyme disease. May 2023 [internet publication].Полный текст

Mead P, Petersen J, Hinckley A. Updated CDC recommendation for serologic diagnosis of lyme disease. MMWR Morb Mortal Wkly Rep. 2019 Aug 16;68(32):703.Полный текст  Аннотация

Mygland A, Ljøstad U, Fingerle V, et al; European Federation of Neurological Societies. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol. 2010 Jan;17(1):8-16;e1-4.Полный текст  Аннотация

National Institute for Health and Care Excellence. Lyme disease. Oct 2018 [internet publication].Полный текст

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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