Resumo
Definição
Анамнез и осмотр
Ключевые диагностические факторы
- headache
- palpitations
- diaphoresis
- hypertension
- hypertensive retinopathy
- pallor
- impaired glucose tolerance/diabetes mellitus
- family history of endocrine disorders
- history of prior pheochromocytoma
- tachyarrhythmias and myocardial infarction
- panic attacks or a "sense of doom"
Другие диагностические факторы
- orthostatic hypotension
- hypercalcemia
- Cushing syndrome
- diarrhea
- fever
- papilledema
- abdominal masses
- tremors
Факторы риска
- multiple endocrine neoplasia type 2 (MEN2)
- Von Hippel-Lindau (VHL) disease
- SDHB, SDHC, and SDHD gene mutations
- neurofibromatosis type 1 (NF1)
Диагностические исследования
Исследования, которые показаны в первую очередь
- plasma free metanephrines or 24-hour urine fractionated metanephrines and normetanephrines
- genetic testing
Tests to avoid
- plasma catecholamines
Исследования, проведение которых нужно рассмотреть
- CBC
- serum calcium
- serum potassium
- chromogranin A
- clonidine suppression test
- CT scan of the abdomen and pelvis
- MRI of the abdomen and pelvis
- 18F-fluorodeoxyglucose (18F-FDG) PET/CT or somatostatin receptor-targeted (SSTR) PET/CT with 68Ga-DOTATATE tracer
- I-123 metaiodobenzylguanidine (MIBG) scintigraphy
Алгоритм лечения
hypertensive crisis
without hypertensive crisis
Составители
Авторы
Bridget Sinnott, MD
Professor of Medicine
Medical College of Georgia
Augusta
GA
Раскрытие информации
BS declares that she has no competing interests.
Выражение благодарностей
Dr Bridget Sinnott would like to gratefully acknowledge Dr Sidhbh Gallagher, a previous contributor to this topic.
Раскрытие информации
SG declares that she has no competing interests.
Рецензенты
Betul A. Hatipoglu, MD
Clinical Endocrinologist and Research Scientist
Department of Endocrinology, Diabetes, and Metabolism
Cleveland Clinic
Cleveland
OH
Раскрытие информации
BAH declares that she has no competing interests.
Список литературы
Основные статьи
Neumann HPH, Young WF Jr, Eng C. Pheochromocytoma and paraganglioma. N Engl J Med. 2019 Aug 8;381(6):552-65. Аннотация
Fishbein L, Del Rivero J, Else T, et al. The North American Neuroendocrine Tumor Society consensus guidelines for surveillance and management of metastatic and/or unresectable pheochromocytoma and paraganglioma. Pancreas. 2021 Apr 1;50(4):469-93.Полный текст Аннотация
National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: neuroendocrine and adrenal tumors [internet publication].Полный текст
Kunz PL, Reidy-Lagunes D, Anthony LB, et al; North American Neuroendocrine Tumor Society. Consensus guidelines for the management and treatment of neuroendocrine tumors. Pancreas. 2013 May;42(4):557-77.Полный текст Аннотация
Plouin PF, Amar L, Dekkers OM, et al; Guideline Working Group. European Society of Endocrinology clinical practice guideline for long-term follow-up of patients operated on for a phaeochromocytoma or a paraganglioma. Eur J Endocrinol. 2016 May;174(5):G1-10.Полный текст Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Отличия
- Anxiety and panic attacks
- Essential or intractable hypertension
- Hyperthyroidism
Больше ОтличияРекомендации
- NCCN clinical practice guidelines in oncology: neuroendocrine and adrenal tumors
- American Association of Endocrine Surgeons guidelines for adrenalectomy
Больше Рекомендации
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