A flavivirus infection of the central nervous system characterised by a biphasic meningoencephalitis.
Transmission is usually by hard ticks of the Ixodes genus. It can also be acquired from consumption of raw (unpasteurised) milk or dairy products.
Disease onset is 4 to 28 days after a bite from an infected tick. Diagnosis is made based on immune status; seasonality; geographical, animal, and arthropod exposures; clinical findings; and radiographic abnormalities.
Treatment consists of supportive care and management of complications. Aciclovir is given empirically until herpes simplex/varicella zoster infection is ruled out.
Most patients recover fully without long-term sequelae.
Four widely used vaccines in paediatric and adult populations are available in Canada, Europe, and Russia.
Tick-borne encephalitis (TBE) is a flavivirus infection of the central nervous system, characterised by a biphasic meningoencephalitis. It is transmitted usually by hard ticks of the Ixodes genus. Disease onset is 4 to 28 days after a bite from an infected tick. TBE can also be acquired from consumption of raw (unpasteurised) milk or dairy products.
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School of Pharmacy and Biomedical Science
University of Portsmouth
AMC declares that he has no competing interests.
Consultant Infectious Diseases Physician
The James Cook University Hospital
JW declares that he has no competing interests.
Your Excellent Health Service
CE runs a private travel clinic.
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