Schizoaffective disorder

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თეორია 
დიაგნოზი 
მართვა 
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შედით სისტემაში ან გამოიწერეთ BMJ Best Practice

ბოლო მიმოხილვა: 8 Dec 2025

ბოლო განახლება: 27 Jul 2022

Schizoaffective disorder has features of both schizophrenia and mood disorders.

The lifetime prevalence is in the range of 0.32% to 1.1%.

The depressive type of schizoaffective disorder is more common in older patients, whereas the bipolar type is more common in younger patients.

Patients have a better prognosis than patients with schizophrenia but a worse prognosis than patients with mood disorder.

Patients tend to have a non-deteriorating course and better response to mood stabiliser medications than patients with schizophrenia.

Patients with schizoaffective disorder are a heterogeneous group with a variable predominance of schizophrenia and affective disorder symptoms.

განსაზღვრება

Schizoaffective disorder is an illness defined by a course that combines significant affective and psychotic symptoms. The Diagnostic and statistical manual of mental disorders (DSM) definition requires the presence of schizophrenia symptoms concurrent with the mood symptoms (depression or mania), and lasting for a considerable part of a 1-month period. Schizoaffective disorder is further classified as bipolar type (when manic symptoms are prominent; major depressive episodes may also occur) or depressive type (when only schizophrenia and major depressive symptoms have been present).[1]

The World Health Organization International statistical classification of diseases and related health problems, 11th revision (ICD-11) definition requires the presence of prominent affective and psychotic symptoms, either at the same time or within a few days of each other.[2] A schizoaffective episode is diagnosed only when the patient does not meet criteria for either schizophrenia or a depressive or manic episode.

ანამნეზი და გასინჯვა

ძირითადი დიაგნოსტიკური ფაქტორები

positive symptoms
negative symptoms
disorder of perception
delusions
disturbances in emotions
incongruent affect
disorders of stream and form of thought
cognitive abnormalities
deficit symptoms
major depressive episodes
manic episodes

სრული ტექსტი

სხვა დიაგნოსტიკური ფაქტორები

neurological deficit
family history
functional impairment
disorders of behaviour

სრული ტექსტი

რისკფაქტორები

family history of schizophrenia
substance use
age of the father at patient's birth
psychological stress
environment

სრული ტექსტი

დიაგნოსტიკური კვლევები

1-ად შესაკვეთი გამოკვლევები

urine drug screen
sexually transmitted disease screening
full blood count
thyroid function tests

სრული ტექსტი

გასათვალისწინებელი კვლევები

laboratory studies to exclude organic causes
CT/MRI head
electroencephalogram (EEG)

სრული ტექსტი

მკურნალობის ალგორითმი

მწვავე

acute psychotic episode

მიმდინარე

multiple-episode disorder

კონტრიბუტორები

ავტორები

Adrian Preda, MD

Professor of Clinical Psychiatry

Department of Psychiatry and Human Behavior

University of California, Irvine School of Medicine

Irvine

გაფრთხილება:

AP was paid for consultancy work for GLG and Guidepoint.

Robert G. Bota, MD

Associate Clinical Professor of Psychiatry

University of California

Irvine

გაფრთხილება:

RGB declares that he has no competing interests.

მადლიერება

Dr Adrian Preda and Dr Robert G. Bota would like to gratefully acknowledge Dr Bao-Nhan Benjamin Nguyen, who contributed to the updating of this topic.

გაფრთხილება:

BN declares that he has no competing interests.

რეცენზენტები

Kemal Sagduyu, MD

Professor of Psychiatry

University of Missouri Kansas City

Kansas City

Раскрытие информации

KS declares that he has no competing interests.

William T. Regenold, MDCM

Associate Professor of Psychiatry

University of Maryland School of Medicine

Baltimore

Раскрытие информации

WTR declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Abrams DJ, Rojas DC, Arciniegas DB. Is schizoaffective disorder a distinct categorical diagnosis? A critical review of the literature. Neuropsychiatr Dis Treat. 2008 Dec;4(6):1089-109.Полный текст Аннотация

Harrow M, Grossman LS, Herbener ES, et al. Ten-year outcome: patients with schizoaffective disorders, schizophrenia, affective disorders and mood-incongruent psychotic symptoms. Br J Psychiatry. 2000 Nov;177:421-6.Полный текст Аннотация

Cheniaux E, Landeira-Fernandez J, Versiani M. The diagnoses of schizophrenia, schizoaffective disorder, bipolar disorder and unipolar depression: interrater reliability and congruence between DSM-IV and ICD-10. Psychopathology. 2009;42(5):293-8. Аннотация

Jäger M, Haack S, Becker T, et al. Schizoaffective disorder: an ongoing challenge for psychiatric nosology. Eur Psychiatry. 2011 Apr;26(3):159-65. Аннотация

Turner DT, van der Gaag M, Karyotaki E, et al. Psychological interventions for psychosis: a meta-analysis of comparative outcome studies. Am J Psychiatry. 2014 May;171(5):523-38. Аннотация

National Institute for Health and Care Excellence. Psychosis and schizophrenia in adults: prevention and management. March 2014 [internet publication].Полный текст

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

Отличия
- Schizophrenia
- Substance-induced psychotic disorder
- Dementia with psychosis
Больше Отличия
Рекомендации
- International statistical classification of diseases and related health problems, 11th revision (ICD-11)
- Diagnostic and statistical manual, 5th edition, text revision (DSM-5-TR)
Больше Рекомендации
Лифлеты для пациента
Schizoaffective disorder
Больше Лифлеты для пациента
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Использование этого контента попадает под действие нашего заявления об отказе от ответственности

Schizoaffective disorder

შეჯამება

განსაზღვრება

ანამნეზი და გასინჯვა

ძირითადი დიაგნოსტიკური ფაქტორები

სხვა დიაგნოსტიკური ფაქტორები

რისკფაქტორები

დიაგნოსტიკური კვლევები

1-ად შესაკვეთი გამოკვლევები

გასათვალისწინებელი კვლევები

მკურნალობის ალგორითმი

acute psychotic episode

multiple-episode disorder

კონტრიბუტორები

ავტორები

Adrian Preda, MD

გაფრთხილება:

Robert G. Bota, MD

გაფრთხილება:

მადლიერება

გაფრთხილება:

რეცენზენტები

Kemal Sagduyu, MD

Раскрытие информации

William T. Regenold, MDCM

Раскрытие информации

Peer reviewer acknowledgements

Disclosures

Список литературы

Основные статьи

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

Отличия

Рекомендации

Лифлеты для пациента

Войдите в учетную запись или оформите подписку, чтобы получить полноценный доступ к BMJ Best Practice

Войдите в учетную запись или оформите подписку, чтобы получить полноценный доступ к BMJ Best Practice

Войдите в учетную запись, чтобы получить полноценный доступ к BMJ Best Practice