Summary
Definition
History and exam
Key diagnostic factors
- motor weakness
- loss of fine motor coordination
- spasticity
- paresthesia, numbness, dysesthesia
- hyperreflexia and ankle clonus
- pathologic reflexes
- contractures
- loss of perianal sensation, voluntary anal contraction and anal tone
- autonomic dysreflexia
- syrinx
Other diagnostic factors
- central (midline) pain
- girdle pain
- musculoskeletal or visceral pain
- unsteady gait
- urinary incontinence or retention
- constipation
- sexual dysfunction
- nonspecific malaise
- radicular pain
Risk factors
- spinal cord trauma or ischemia
- higher-level spinal cord lesion
- extremes of age
- narrow spinal canal
- male sex
Diagnostic tests
Tests to consider
- MRI spine
- EMG
- urodynamic studies
- bladder ultrasound
- renal ultrasound
- micturition cystourethrogram
- bone densitometry (DEXA)
- laboratory evaluation
Treatment algorithm
progressive neurologic deficit
stable neurologic status
Contributors
Authors
Cristina Sadowsky, MD
Clinical Director
International Center for Spinal Cord Injury
Kennedy Krieger Institute
Associate Professor Physical Medicine and Rehabilitation
Johns Hopkins School of Medicine
Baltimore
MD
Disclosures
CS has received travel reimbursement for presentations on topics including myelopathies, spinal cord injury, and pediatric paralysis from Kennedy Krieger Institute and ALD Connect (a nonprofit organization). CS has served as a Board Member for the Society for Brain Mapping and Therapeutics from 2020-2023. She has been a board member for the Steel Assembly since 2022. CS is an author of a number of references cited in this topic.
Travis Edmiston, MD
Assistant Professor for Physical Medicine and Rehabilitation
International Center for Spinal Cord Injury
Kennedy Krieger Institute
Baltimore
MD
Disclosures
TE declares that he has no competing interests.
Acknowledgements
Dr Cristina Sadowsky and Dr Travis Edmiston would like to gratefully acknowledge Dr Kenneth Casey and Dr Jwalant Mehta, previous contributors to this topic.
Disclosures
KC and JM declare that they have no competing interests.
Peer reviewers
Steven Kirshblum, MD
Medical Director and Director of Spinal Cord Injury Services
Kessler Institute for Rehabilitation
West Orange
Professor
University of Medicine and Dentistry of New Jersey/New Jersey Medical School
Newark
NJ
Disclosures
SK declares that he has no competing interests.
Deborah Short, MRCP
Consultant in Rehabilitation Medicine
Robert Jones and Agnes Hunt Hospital
Oswestry
UK
Disclosures
DS declares that she has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Royal College of Physicians. Chronic spinal cord injury: management of patients in acute hospital settings. Feb 2008 [internet publication].Full text
Loh E, Mirkowski M, Agudelo AR, et al. The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update. Spinal Cord. 2022 Jun;60(6):548-66.Full text Abstract
Obstetric management of patients with spinal cord injuries: ACOG Committee opinion summary, number 808. Obstet Gynecol. 2020 May;135(5):1247-49.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Noncompressive myelopathy
- Compressive myelopathy
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- Rehabilitation for chronic neurological disorders including acquired brain injury
- Urinary incontinence in neurological disease: assessment and management
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