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Chronic spinal cord injury

Evidence last reviewed: 22 Apr 2026
Topic last updated: 14 May 2026

Summary

Definition

History and exam

Key diagnostic factors

  • motor weakness
  • loss of fine motor coordination
  • spasticity
  • paresthesia, numbness, dysesthesia
  • hyperreflexia and ankle clonus
  • pathologic reflexes
  • contractures
  • loss of perianal sensation, voluntary anal contraction and anal tone
  • autonomic dysreflexia
  • syrinx
Full details

Other diagnostic factors

  • central (midline) pain
  • girdle pain
  • musculoskeletal or visceral pain
  • unsteady gait
  • urinary incontinence or retention
  • constipation
  • sexual dysfunction
  • nonspecific malaise
  • radicular pain
Full details

Risk factors

  • spinal cord trauma or ischemia
  • higher-level spinal cord lesion
  • extremes of age
  • narrow spinal canal
  • male sex
Full details

Diagnostic tests

Tests to consider

  • MRI spine
  • EMG
  • urodynamic studies
  • bladder ultrasound
  • renal ultrasound
  • micturition cystourethrogram
  • bone densitometry (DEXA)
  • laboratory evaluation
Full details

Treatment algorithm

ACUTE

progressive neurologic deficit

stable neurologic status

Contributors

Authors

Cristina Sadowsky, MD

Clinical Director

International Center for Spinal Cord Injury

Kennedy Krieger Institute

Associate Professor Physical Medicine and Rehabilitation

Johns Hopkins School of Medicine

Baltimore

MD

Disclosures

CS has received travel reimbursement for presentations on topics including myelopathies, spinal cord injury, and pediatric paralysis from Kennedy Krieger Institute and ALD Connect (a nonprofit organization). CS has served as a Board Member for the Society for Brain Mapping and Therapeutics from 2020-2023. She has been a board member for the Steel Assembly since 2022. CS is an author of a number of references cited in this topic.

Travis Edmiston, MD

Assistant Professor for Physical Medicine and Rehabilitation

International Center for Spinal Cord Injury

Kennedy Krieger Institute

Baltimore

MD

Disclosures

TE declares that he has no competing interests.

Acknowledgements

Dr Cristina Sadowsky and Dr Travis Edmiston would like to gratefully acknowledge Dr Kenneth Casey and Dr Jwalant Mehta, previous contributors to this topic.

Disclosures

KC and JM declare that they have no competing interests.

Peer reviewers

Steven Kirshblum, MD

Medical Director and Director of Spinal Cord Injury Services

Kessler Institute for Rehabilitation

West Orange

Professor

University of Medicine and Dentistry of New Jersey/New Jersey Medical School

Newark

NJ

Disclosures

SK declares that he has no competing interests.

Deborah Short, MRCP

Consultant in Rehabilitation Medicine

Robert Jones and Agnes Hunt Hospital

Oswestry

UK

Disclosures

DS declares that she has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Royal College of Physicians. Chronic spinal cord injury: management of patients in acute hospital settings. Feb 2008 [internet publication].Full text

Loh E, Mirkowski M, Agudelo AR, et al. The CanPain SCI clinical practice guidelines for rehabilitation management of neuropathic pain after spinal cord injury: 2021 update. Spinal Cord. 2022 Jun;60(6):548-66.Full text  Abstract

Obstetric management of patients with spinal cord injuries: ACOG Committee opinion summary, number 808. Obstet Gynecol. 2020 May;135(5):1247-49.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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