Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- sudden-onset focal neurologic deficit
- seizures
- reduced conscious level
Outros fatores diagnósticos
- sudden-onset headache
- nausea
- vomiting
- confusion
- gradual-onset headaches
- hypertension
- coma
- gradual-onset focal neurologic deficit
- cognitive dysfunction
Fatores de risco
- familial (malformation)
- previous hemorrhages (risk of hemorrhage)
- drug abuse (risk of hemorrhage)
- abnormal venous drainage (risk of hemorrhage)
- small AVMs (risk of hemorrhage)
- posterior fossa and deep AVMs (risk of hemorrhage)
- coexisting aneurysms (risk of hemorrhage)
- pregnancy (risk of hemorrhage)
- hypertension (risk of hemorrhage)
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- brain CT
- brain MRI
Investigações a serem consideradas
- brain digital subtraction angiogram
- brain CT angiogram
- brain magnetic resonance angiogram
- CBC
- clotting screen and group
- electrolyte panel
- drug toxicology screen
- functional imaging
- superselective Wada
- neuropsychology
- perfusion studies
- electroencephalogram
- visual fields
Novos exames
- 4D CT angiography (CTA)/magnetic resonance angiography (MRA)
Algoritmo de tratamento
associated hematoma if significant mass effect
not surgical candidate
surgical candidate
pregnant
Colaboradores
Autores
Mervyn Lim, MBBS, MRCS, MPH
Senior Resident
Department of Neurosurgery
National University Health System
Singapore
Declarações
ML declares that he has no competing interests.
Leonard Yeo, MBBS, MRCP, MMed, ASN
Senior Consultant
Department of Medicine (Neurology)
National University Health System
Assistant Professor
Yong Loo Lin School of Medicine
National University of SIngapore
Singapore
Declarações
LY declares that he has no competing interests.
Benjamin Tan, MBBS, MRCP, MMed
Associate Consultant
Department of Medicine (Neurology)
National University Health System
Singapore
Declarações
BT declares that he has no competing interests.
Adriel Leong, MBBS, MRCS
Senior Resident
Department of Neurosurgery
National University Health System
Singapore
Declarações
AL declares that he has no competing interests.
Audrey Tan, BSc Medical Sciences (Hons), MBChB, MRCS
Senior Resident
Department of Neurosurgery
National University Health System
Singapore
Declarações
AT declares that he has no competing interests.
Pervinder Bhogal, MBBS
Consultant
Department of Radiology
St Bartholomew's and The Royal London Hospital
London
UK
Declarações
PB declares that he has no competing interests.
Yang Cunli, MBBS, FRCR, MMed, FAMS
Senior Consultant
Department of Diagnostic Imaging
National University Health System
Assistant Professor
Yong Loo Lin School of Medicine
National University of Singapore
Singapore
Declarações
YC declares that he has no competing interests.
Anil Gopinathan, MBBS, MD, DNB, FRCR, FAMS
Head of Division of Interventional Radiology
Senior Consultant
Department of Diagnostic Imaging
National University Health System
Assistant Professor
Yong Loo Lin School of Medicine
National University of Singapore
Singapore
Declarações
AG declares that he has no competing interests.
Agradecimentos
Dr Leonard Yeo, Dr Benjamin Tan, Dr Adriel Leong, Dr Audrey Tan, Dr Mervyn Lim, Dr Pervinder Bhogal, Dr Yang Cunli, and Dr Anil Gopinathan would like to gratefully acknowledge Dr Charles Matouk, Dr Catherine E. Gilkes, and Dr Richard J. Edwards, previous contributors to this topic, and the additional contribution of Dr Branden Cord and Dr Ryan Hebert.
Declarações
CM, CEG, and RJE declare that they have no competing interests.
Revisores
Bernhard Meyer, MD
Chairman
Professor of Neurosurgery
Department of Neurosurgery
Technical University of Munich
Munich
Germany
Declarações
BM declares that he has no competing interests.
Michael Chen, MD
Assistant Professor of Neurology
Neurosurgery and Radiology
Rush University Medical Center
Chicago
IL
Declarações
MC declares that he has no competing interests.
Jae H. Choi, MD
Research Director
Stroke Center/The Neurological Institute
Columbia-Presbyterian Medical Center
New York
NY
Declarações
JHC declares that he has no competing interests.
Créditos aos pareceristas
Os tópicos do BMJ Best Practice são constantemente atualizados, seguindo os desenvolvimentos das evidências e das diretrizes. Os pareceristas aqui listados revisaram o conteúdo pelo menos uma vez durante a história do tópico.
Declarações
As afiliações e declarações dos pareceristas referem--se ao momento da revisão.
Referências
Principais artigos
Al-Shahi R, Warlow C. A systematic review of the frequency and prognosis of arteriovenous malformations of the brain in adults. Brain. 2001 Oct;124(Pt 10):1900-26.Texto completo Resumo
Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. J Neurosurg. 1986 Oct;65(4):476-83. Resumo
Greenberg SM, Ziai WC, Cordonnier C, et al. 2022 Guideline for the management of patients with spontaneous intracerebral hemorrhage: a guideline from the American Heart Association/American Stroke Association. Stroke. 2022 Jul;53(7):e282-361.Texto completo Resumo
Derdeyn CP, Zipfel GJ, Albuquerque FC, et al. Management of brain arteriovenous malformations: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2017 Aug;48(8):e200-24. Resumo
Zuurbier SM, Al-Shahi Salman R. Interventions for treating brain arteriovenous malformations in adults. Cochrane Database Syst Rev. 2019 Sep 10;9(9):CD003436.Texto completo Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
Diagnósticos diferenciais
- Cerebral aneurysm
- Cavernous hemangioma
- Dural arteriovenous fistula
Mais Diagnósticos diferenciaisDiretrizes
- Guidelines for the management of spontaneous intracerebral hemorrhage
- Clinical practice guidelines for management of brain arteriovenous malformations in eloquent areas
Mais DiretrizesFolhetos informativos para os pacientes
Stroke: treatment
Mais Folhetos informativos para os pacientes
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