Assessment of liver dysfunction

Last reviewed: 6 Jan 2023
Last updated: 31 Jan 2023




  • Hepatitis C virus infection
  • Hepatitis B virus infection
  • Hepatitis A virus infection
  • Alcohol-related liver disease
  • Paracetamol overdose
  • Non-paracetamol medications or dietary supplements
  • Non-alcoholic fatty liver disease
  • Gilbert's syndrome
  • Haemochromatosis
  • Choledocholithiasis
Full details


  • Hepatitis E
  • Hepatitis D
  • Epstein-Barr virus infection
  • Herpes simplex virus infection
  • Cytomegalovirus infection
  • HIV infection
  • Sepsis
  • Extrapulmonary tuberculosis
  • Toxins
  • Alpha-1 antitrypsin deficiency
  • Wilson's disease
  • Autoimmune hepatitis
  • Primary biliary cholangitis
  • Primary sclerosing cholangitis
  • Hepatocellular carcinoma
  • Liver metastases
  • Pancreatic cancer
  • Cholangiocarcinoma
  • Hodgkin's lymphoma
  • Non-Hodgkin's lymphoma
  • Shock
  • Portal vein thrombosis
  • Budd-Chiari syndrome
  • Intrahepatic cholestasis of pregnancy
  • Haemolysis, elevated liver enzymes, low platelets (HELLP) syndrome
  • Acute fatty liver of pregnancy
Full details



Stevan A. Gonzalez, MD, MS

Associate Professor

Department of Internal Medicine

TCU and UNTHSC School of Medicine

Medical Director of Liver Transplantation

Annette C. and Harold C. Simmons Transplant Institute

Baylor Scott & White All Saints Medical Center

Fort Worth



SAG declares that he has no competing interests.


Dr Stevan A. Gonzalez would like to gratefully acknowledge Dr Jeremy Cobbold, Dr William D. Carey, and Dr Achuthan Sourianarayanane, the previous contributors to this topic.


WDC is an author of a number of references cited in this topic. JC and AS declare that they have no competing interests.

Peer reviewers

Joseph K. Lim, MD

Assistant Professor of Medicine


Yale Viral Hepatitis Program

Section of Digestive Diseases

Yale School of Medicine

New Haven



JKL declares that he has no competing interests.

Philip Newsome, PhD, FRCPE

Senior Lecturer in Hepatology & Honorary Consultant Physician

Liver Research Group

Institute of Biomedical Research

The Medical School

University of Birmingham




PN declares that he has no competing interests.

Marlyn Mayo, MD

Associate Professor of Medicine

Division of Digestive and Liver Diseases

University of Texas Southwestern Medical Center




MM is an author of a reference cited in this topic.

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