Thyroid function testing
Summary
Detalhes
- Thyroid hormone production
- Thyroid hormone-binding proteins
- Indications for TFTs: general considerations
- Known thyroid dysfunction and preconception
- Screening for thyroid dysfunction during pregnancy
- Screening for congenital hypothyroidism
- TFTs
- Low TSH - associated with a high FT4 and/or FT3
- Low TSH - associated with a low FT4 and/or FT3
- Low TSH - associated with a normal FT4 and/or FT3
- High TSH - associated with a high FT4 and/or FT3
- High TSH - associated with a low FT4 and/or FT3
- High TSH - associated with a normal FT4 and/or FT3
- Normal TSH - associated with a low FT4 and/or FT3
- Drug effects
Colaboradores
Autores
Joel Ehrenkranz, MD
Associate Professor
Division of Chemistry and Chemical Engineering
California Institute of Technology
Pasadena
CA
Declarações
JE declares that he has served on a writing group for the American Thyroid Association which drafted an article on thyroid function testing and was submitted for publication to the journal Thyroid.
Agradecimentos
Dr Joel Ehrenkranz would like to gratefully acknowledge Dr Mae Sheikh-Ali, Dr Harshit Shah, Dr Melanie Thomas, Dr Anna Szafran-Swietlik, Dr Sandra Mesliniene, Dr Emad Naem, and Dr Abdul-Razzak Alamir, previous contributors to this topic. HS, MT, AS-S, SM, EN, and A-RA declare that they have no competing interests. MS-A declares she is a speaker for IBSA and AbbVie. Both have brand names for levothyroxine (LT4) medication.
Revisores
Ronald Merrell, MD
Professor of Surgery
Virginia Commonwealth University
Richmond
VA
Declarações
RM declares that he has no competing interests.
Georg Hennemann, MD
Professor of Medicine and Endocrinology
Medical Center Spijkenisse
The Hague
The Netherlands
Declarações
Not disclosed.
Simon Pearce, MD
Professor of Endocrinology
Newcastle University
Endocrine Unit
Royal Victoria Infirmary
Newcastle upon Tyne
UK
Declarações
SP declares that he has no competing interests.
V.S. Schneider, MD
Clinical Associate Professor of Medicine
Uniformed Services University of the Health Sciences
Bethesda
MD
MA and Senior Medical Advisor
NASA Headquarters
Washington
DC
Declarações
VSS declares that he has no competing interests.
Créditos aos pareceristas
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Declarações
As afiliações e declarações dos pareceristas referem--se ao momento da revisão.
Referências
Principais artigos
Ross DS, Burch HB, Cooper DS, et al. 2016 American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis. Thyroid. 2016 Oct;26(10):1343-1421.Texto completo Resumo
Garber JR, Cobin RH, Gharib H, et al. Clinical practice guidelines for hypothyroidism in adults co-sponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Thyroid. 2012 Dec;22(12):1200-35.Texto completo Resumo
Alexander EK, Pearce EN, Brent GA, et al. 2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid. 2017 Mar;27(3):315-89.Texto completo Resumo
National Institute for Health and Care Excellence. Thyroid disease: assessment and management. 2023 [internet publication].Texto completo
Artigos de referência
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