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Pityriasis lichenoides

最后审阅: 17 Aug 2025
最后更新: 10 Dec 2024

小结

定义

病史和体格检查

关键诊断因素

  • acute to subacute recurrent skin eruption
  • polymorphic, generalized, nonpruritic skin eruption
完整详情

其他诊断因素

  • scars or pigment changes
  • immunosuppression
  • recent illness
  • family history of pityriasis lichenoides
  • headache
  • myalgias/arthralgias
  • malaise
  • burning/pruritus
  • multiorgan failure
完整详情

危险因素

  • childhood to early adult age
  • male sex
  • HIV
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诊断性检查

首要检查

  • dermoscopy
  • skin biopsy
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需考虑的检查

  • antistreptolysin titers
  • Epstein-Barr virus IgM/IgG viral capsid antigen and nuclear antigen antibody
  • monospot or heterophil antibody test
  • hepatitis B surface antigen, antisurface antibody, and anticore IgM
  • hepatitis C virus antibody
  • HIV screening
  • rapid plasma reagin
  • throat cultures
  • toxoplasma Sabin-Feldman dye test, indirect immunofluorescence/hemagglutination
  • erythrocyte sedimentation rate
  • CRP
  • serum LDH
  • WBC count
  • serum albumin
完整详情

治疗流程

持续性治疗

mild to moderate disease

severe disease or treatment resistance

撰稿人

作者

Amy Musiek, MD

Professor of Dermatology

Division of Dermatology

Washington University School of Medicine in St. Louis

St. Louis

MO

利益声明

AM is a paid lecturer in cutaneous T-cell lymphoma for Dermatology Week, is the author of the UpToDate article on Pityriasis lichenoides chronica, and is an investigator for multiple industry sponsored studies all unrelated to pityriasis lichenoides.

鸣谢

Dr Amy Musiek would like to gratefully acknowledge Dr Amer Khachemoune and Dr Marianna Blyumin-Karasik, previous contributors to this topic.

利益声明

AK and MB-K declare that they have no competing interests.

同行评议者

Andrew D. Lee, MD

Resident

Department of Dermatology

Wake Forest University School of Medicine

Winston-Salem

NC

利益声明

ADL declares that he has no competing interests.

Abdulhafez Selim, MD

Assistant Professor

King Fahd University of Petroleum and Minerals

Dhahran

Saudi Arabia

利益声明

AS declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Khachemoune A, Blyumin ML. Pityriasis lichenoides: pathophysiology, classification, and treatment review. Am J Clin Dermatol. 2007;8(1):29-36. 摘要

Bowers S, Warshaw EM. Pityriasis lichenoides and its subtypes. J Am Acad Dermatol. 2006 Oct;55(4):557-72; quiz 573-6. 摘要

Bellinato F, Maurelli M, Gisondi P, et al. A systematic review of treatments for pityriasis lichenoides. J Eur Acad Dermatol Venereol. 2019 Nov;33(11):2039-49. 摘要

Jung F, Sibbald C, Bohdanowicz M, et al. Systematic review of the efficacies and adverse effects of treatments for pityriasis lichenoides. Br J Dermatol. 2020 Dec;183(6):1026-32. 摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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