A rare inflammatory skin disease with unclear aetiology.
It manifests as widespread polymorphic papulosquamous dermatitis that varies in a spectrum of clinical presentations and course. The course of pityriasis lichenoides is unpredictable.
Very rarely, it may progress to the cutaneous form of lymphoma.
It is optimally managed with a combination of topical, light, and systemic therapies.
Pityriasis lichenoides is an uncommon, acquired, idiopathic skin condition. It is a challenging disorder to diagnose, categorise, and treat due to its varied presentation and uncertain course. Pityriasis lichenoides manifests as diffuse polymorphic, papulosquamous dermatitis that varies in severity, temporal onset and development, and prognosis. The scope of presentations is classified along a continuum of 3 subtypes, including pityriasis lichenoides et varioliformis acuta, pityriasis lichenoides chronica, and febrile ulceronecrotic Mucha-Habermann's disease.
History and exam
- anti-streptolysin titres
- Epstein-Barr virus IgM/IgG viral capsid antigen and nuclear antigen antibody
- monospot or heterophil antibody test
- hepatitis B surface antigen, anti-surface antibody, and anti-core IgM
- hepatitis C virus antibody
- HIV screening
- rapid plasma reagin
- throat cultures
- toxoplasma Sabin-Feldman's dye test, indirect immunofluorescence/haemagglutination
- erythrocyte sedimentation rate
- serum LDH
- WBC count
- serum albumin
Amor Khachemoune, MD, CWS
Clinical Instructor in Dermatology
SUNY Downstate Medical Center
AK declares that he has no competing interests.
Marianna Blyumin-Karasik, MD
Department of Dermatology & Cutaneous Surgery
University of Miami
MB-K declares that she has no competing interests.
Andrew D. Lee, MD
Department of Dermatology
Wake Forest University School of Medicine
ADL declares that he has no competing interests.
Abdulhafez Selim, MD
King Fahd University of Petroleum and Minerals
AS declares that he has no competing interests.
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