Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- diarrhoea
- history of travel, contact with contaminated food, or contact with infected person
Outros fatores diagnósticos
- abdominal pain or discomfort
- volume depletion
- fever
- nausea/vomiting
- anorexia
- lethargy
Fatores de risco
- ingestion of contaminated food products or water
- travel
- poor hygiene practices
- infantile or advanced age (<5 years and >60 years)
- contact history
- immunocompromised state
- contact with infected animals
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- stool cultures
- FBC
- renal function and electrolytes
Investigações a serem consideradas
- identification of Shiga toxin-producing E coli infection
- blood cultures
- inflammatory markers (CRP and/or erythrocyte sedimentation rate)
- abdominal x-ray
- endoscopy
- abdominal CT scan
Algoritmo de tratamento
all patients
confirmed enterotoxigenic positive
confirmed enterohaemorrhagic positive
other Escherichia coli serotypes
Colaboradores
Autores
Eli D. Ehrenpreis, MD, FACG, AGAF
Associate Director for Research
Internal Medicine Residency
Advocate Lutheran General Hospital
Park Ridge
IL
Declarações
EDE is a CEO for E2Bio Life Sciences LLC and G.I. Pharmaceuticals Inc. E2Bio Life Sciences LLC has developed Bocaliner, an FDA-registered class 1 medical device designed to enhance the efficacy of topical medicines applied to the oral cavity. G.I. Pharmaceuticals Inc. has medical treatments for oral leukoplakia designed to prevent oral cancer, and a new medicine for anal pruritis.
Agradecimentos
Dr Eli D. Ehrenpreis would like to gratefully acknowledge the assistance of Dr Thomas Adam Wichelmann, who contributed to this update. Dr Ehrenpreis would also like to acknowledge Dr Alexandra Kent and Professor Satis Keshav, the previous contributors to this topic.
Declarações
TAW, AK, and SK declare that they have no competing interests.
Revisores
Andrew Poullis, BSc, MBBS, MD, FRCP
Consultant Gastroenterologist
St George’s Hospital
London
UK
Declarações
AP declares that he has no competing interests.
Fiona Cooke, MA, PhD, MSc, FRCPath, MRCP, DTM&H
Research Fellow and Medical Microbiologist
Wellcome Trust Sanger Institute
Department of Microbiology
Addenbrooke's Hospital
Cambridge
UK
Declarações
FC declares that she has no competing interests.
Houssam E. Mardini, MD, MPH, FACP
Voluntary Assistant Professor of Medicine
Digestive Health & Nutrition Center of Ashland
Ashland
KY
Declarações
HEM declares that he has no competing interests.
Créditos aos pareceristas
Os tópicos do BMJ Best Practice são constantemente atualizados, seguindo os desenvolvimentos das evidências e das diretrizes. Os pareceristas aqui listados revisaram o conteúdo pelo menos uma vez durante a história do tópico.
Declarações
As afiliações e declarações dos pareceristas referem--se ao momento da revisão.
Referências
Principais artigos
Nataro JP, Kaper JB. Diarrheagenic Escherichia coli. Clin Microbiol Rev. 1998 Jan;11(1):142-201.Texto completo Resumo
Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia coli. Nat Rev Microbiol. 2004 Feb;2(2):123-40.Texto completo Resumo
American Medical Association; American Nurses Association-American Nurses Foundation; Centers for Disease Control and Prevention; Center for Food Safety and Applied Nutrition, Food and Drug Administration; Food Safety and Inspection Service, US Department of Agriculture. Diagnosis and management of foodborne illnesses: a primer for physicians and other health care professionals. MMWR Recomm Rep. 2004 Apr 16;53(RR-4):1-33.Texto completo Resumo
Shane AL, Mody RK, Crump JA, et al. 2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea. Clin Infect Dis. 2017 Nov 29;65(12):e45-e80.Texto completo Resumo
Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 2: preparing international travelers - travelers' diarrhea. May 2023 [internet publication].Texto completo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
Differentials
- Viral gastroenteritis
- Alternative foodborne bacterial gastroenteritis/traveller's diarrhoea
- Amoebiasis
Mais DifferentialsGuidelines
- Infectious diarrhea - guideline for investigation
- E. coli (Escherichia coli) infection
Mais GuidelinesPatient information
Diarrhoea in adults
Diarrhoea in children
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