Last reviewed:September 2019
Last updated:December  2018

Summary

Differentials

Common

  • Eating disorders or female athlete triad
  • Emotional or physical stress
  • Post-contraception with depot medroxyprogesterone
  • Hyperprolactinaemia
  • Polycystic ovary syndrome (PCOS)
  • Idiopathic premature ovarian failure
  • Post-chemoradiation ovarian failure
  • Chromosomal abnormality (Fragile X carrier, Turner's syndrome mosaic)
  • Non-classic congenital adrenal hyperplasia
  • Hypothyroidism

Uncommon

  • Malnutrition or chronic disease state
  • Empty sella syndrome
  • Sheehan's syndrome (postpartum pituitary necrosis)
  • Post-encephalitis
  • Androgen-producing ovarian tumour
  • Autoimmune premature ovarian failure
  • Androgen-producing adrenal tumour
  • Cushing's syndrome
  • Asherman's syndrome
  • Drug-induced

Contributors

Meir Jonathon Solnik

Associate Professor of Obstetrics and Gynaecology

University of Toronto Faculty of Medicine

Head of Gynaecology and Minimally Invasive Surgery

Sinai Health System

Site Chief of Gynaecology

Women’s College Hospital

Toronto

Canada

Disclosures

MJS reports that he is a consultant for Medtronic, and he is on the advisory boards at AbbVie and Allergan. He has also been a moderator for Bayer.

Peer reviewersVIEW ALL

Professor

Department of Obstetrics, Gynecology, and Reproductive Sciences

Vice Chairman

Reproductive Sciences

Director

Division of Reproductive Endocrinology and Infertility

University of Pittsburgh

Pittsburgh

PA

Disclosures

JSS declares that he has no competing interests.

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