Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- upper or lower limb claudication
- absent pulse(s)
- unequal blood pressures
- vascular bruits
- low-grade fever
Other diagnostic factors
- transient ischaemic attack (TIA)
- myalgia
- arthralgia
- weight loss
- fatigue
- dizziness on upper-limb exertion
- hypertension
- stroke
- chest pain
- abdominal pain
- diarrhoea
- shortness of breath
- haemoptysis
- night sweats
- vertigo
- syncope
- headache
- heart murmur
- visual symptoms
- erythema nodosum
- pyoderma gangrenosum
Diagnostic investigations
1st investigations to order
- ESR
- CRP
- computerised tomography angiography (CTA)
- magnetic resonance imaging angiography (MRA)
Investigations to consider
- catheter angiogram
- Doppler ultrasound
- positron emission tomography with radiolabelled fluorodeoxyglucose (PET-FDG)
Treatment algorithm
Contributors
Authors VIEW ALL
Associate Professor of Medicine
Mayo Clinic College of Medicine
Rochester
MN
Disclosures
SRY declares that he was a sub-awardee of a grant from the US Food and Drug Administration for a pilot study of abatacept, a treatment for Takayasu's arteritis. SY is also a member of the steering committee at the Vasculitis Clinical Research Committee.
Professor of Medicine
Mayo Clinic College of Medicine
Rochester
MN
Disclosures
KJW declares that he has no competing interests.
Professor of Medicine
Mayo Clinic College of Medicine
Rochester
MN
Disclosures
ELM declares that he has no competing interests.
Peer reviewers VIEW ALL
Internal Medicine
Hopital Cochin-Paris University
St-Jacques
Paris
France
Disclosures
LPG declares that he has no competing interests.
Department of Medicine
Division of Rheumatology
Mayo Clinic
Rochester
MN
Disclosures
GGH is an author of a reference cited in this monograph. GGH declares that he has no other competing interests.
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