Last reviewed: 6 Nov 2021
Last updated: 14 Jun 2019

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • dyspnoea
  • syncope
  • dizziness
  • CHF/pulmonary oedema
  • embolic manifestations
  • systolic or diastolic murmur
  • tumour plop

Other diagnostic factors

  • weight loss
  • fatigue
  • fever
  • pallor
  • arthralgia
  • Raynaud's phenomenon
  • loud first heart sound
  • opening snap
  • Carney's complex

Risk factors

  • family history of atrial myxoma
  • female sex
  • age 40-60 years

Diagnostic investigations

Investigations to consider

  • erythrocyte sedimentation rate
  • C-reactive protein
  • protein electrophoresis
  • CT scan (chest)
  • MRI scan (chest)
  • biopsy

Treatment algorithm

Contributors

Authors

Syed Wamique Yusuf, MBBS, FRCPI
Syed Wamique Yusuf

Professor of Medicine

Department of Cardiology

University of Texas MD Anderson Cancer Center

Houston

TX

Disclosures

SWY is Co-Director of the American College of Cardiology Cardiovascular Board Review Course, at which he also delivers lectures.

Acknowledgements

Dr Syed Wamique Yusuf would like to gratefully acknowledge the assistance of Dr Daniel J. Lenihan. DJL declares that he has no competing interests.

Peer reviewers

Paul Heidenreich, MD

Associate Professor of Medicine

Stanford University

Stanford

CA

Disclosures

PH declares that he has no competing interests.

Richard Steingart, MD

Chief

Cardiology Service

Memorial Sloan-Kettering Cancer Center

New York

NY

Disclosures

RS declares that he has no competing interests.

Barry Kneale, MD, FRCP

Integrated Lead Cardiologist

Western Sussex Hospitals NHS Trust and Cardiac Department

Worthing Hospital

Worthing

UK

Disclosures

BK declares that he has no competing interests.

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