最近审阅: 26 九月 2020
最近更新: 06 三月 2019

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 下肢力量失衡
  • 下肢肌腱挛缩
  • 动作发展指标推迟
  • 腓肠肌肥大
  • 行走困难及跌倒
  • 肌张力及深腱反射减弱
  • 感觉正常

其他诊断因素

  • Gowers体征
  • 用脚趾走路
  • 肌张力过低
  • 活动过度
  • 大小便失禁
  • 不同程度的精神发育迟滞

诊断性检查

首要检查

  • 血清肌酸激酶 (CK)
  • 基因检测
更多 首要检查

需考虑的检查

  • 肌电图(EMG)
  • 肌肉活检
更多 需考虑的检查

治疗流程

撰稿人

Consultant Paediatric Neurologist

Great Ormond Street Hospital for Children

London

UK

利益声明

PM has received education and travel grants from PTC therapeutics (Ataluren) in 2016 for a conference.

Dr Pinki Munot would like to gratefully acknowledge Dr John R. Bach, Dr Aravindhan Veerapandiyan, and Dr Bilal Saulat, previous contributors to this topic. JRB, AV, and BS declare that they have no competing interests.

同行评议者展开全部内容

Assistant Professor of Medicine

Department of Medicine/Neurology

Duke University Medical Center

Durham

NC

利益声明

LDH-W declares that she has no competing interests.

Associate Professor Neurology and Regenerative Medicine

Wake Forest University Health Sciences

Winston-Salem

NC

利益声明

MKC declares that he has no competing interests.

Consultant Paediatric Neurologist

Great Ormond Street Hospital for Children NHS Trust

London

UK

利益声明

AM has been paid an honorarium for giving lectures at the Imperial College Educative Training Courses for GPs and post-graduate doctors. AM is the lead author of the Cochrane review of corticosteroids in Duchenne muscular dystrophy. He is also the Lead Clinician of the NorthStar Clinical Network for Management of Neuromuscular Disorders in the UK.

Senior Lecturer and Consultant Neurologist

Department of Clinical Neuroscience

UCL Institute of Neurology

London

UK

利益声明

RWO is an author of a reference cited in this topic.

内容使用需遵循免责声明