血小板减少定义为血液循环中的血小板计数较低（<150,000/微升）。 血小板的寿命通常为 5 天左右，并不断更新。 真性血小板减少的原因是骨髓中生成的血小板减少、清除率增加，或较多的血小板阻留在脾脏中。
Weill Cornell Medicine
Pathology and Laboratory Medicine
Division of Immunopathology
JTG declares that she has no competing interests.
Dr Julia T. Geyer would like to gratefully acknowledge Dr Alan E. Lichtin, a previous contributor to this monograph. AEL is on an advisory board and has received research support from Amgen.
Clinical Professor of Medicine
University of Texas Health Science Center
Cancer Care Network of South Texas
RML declares that he has no competing interests.
Clinical Assistant Professor of Medicine
University of Connecticut School of Medicine
JSW has received research support from Amgen, Ligand Pharmaceuticals, and MGI Pharma for clinical studies in immune thrombocytopenic purpura.
Professor of Medicine
Case Western Reserve University School of Medicine
KRM declares that he has no competing interests.