小结
鉴别诊断
常见
- 白血病
- 转移性恶性肿瘤
- 霍奇金淋巴瘤
- 非霍奇金淋巴瘤
- 粟粒性结核
- 弥散性血管内凝血 (DIC)
- 输血后
- 溶血、肝酶升高和低血小板计数 (HELLP) 综合征
- 心肺转流术
- 免疫性血小板减少症 (ITP)
- 系统性红斑狼疮 (SLE)
- 类风湿关节炎
- 抗磷脂综合征
- HIV/AIDS
- 疟疾
- 登革热
- 寨卡病毒感染
- 巨细胞病毒 (cytomegalovirus, CMV)
- 传染性单核细胞增多症
- COVID-19
- 细小病毒 B19
- 脓毒症
- 肝素诱导的血小板减少症 (HIT)
- 抗疟药、抗癫痫药、抗生素或化疗
- 饮酒
- 维生素 B12 缺乏
- 叶酸缺乏症
- 妊娠期血小板减少
- 肝硬化
不常见
- 多发性骨髓瘤
- 骨髓纤维化
- 血栓性血小板减少性紫癜 (TTP)
- 溶血性尿毒症综合征 (HUS)
- 结节病
- 周期性血小板减少症
- Wiskott-Aldrich 综合征
- MYH9 相关障碍，其中包括 May-Hegglin 异常
- Bernard-Soulier 综合征
- Gaucher 病
- 桥本氏甲状腺炎
- 再生障碍性贫血
- 疫苗接种
- 阵发性睡眠性血红蛋白尿 (PNH)
- 假性血小板减少症
- 生殖细胞系 RUNX1 突变引起的家族性血小板病
- 生殖细胞系 ANKRD26 突变引起血小板减少症
- 生殖细胞系 ETV6 突变引起血小板减少症
撰稿人
作者
Julia T. Geyer, MD
Associate Professor
Weill Cornell Medicine
Pathology and Laboratory Medicine
Division of Immunopathology
New York
NY
利益声明
JTG declares that she has no competing interests.
鸣谢
Dr Julia T. Geyer would like to gratefully acknowledge Dr Alan E. Lichtin, a previous contributor to this topic.
利益声明
AEL is on an advisory board and has received research support from Amgen.
同行评议者
Roger M. Lyons, MD, FACP
Clinical Professor of Medicine
University of Texas Health Science Center
San Antonio
Cancer Care Network of South Texas
San Antonio
TX
利益声明
RML declares that he has no competing interests.
Jeffrey S. Wasser, MD
Clinical Assistant Professor of Medicine
University of Connecticut School of Medicine
Farmington
CT
利益声明
JSW has received research support from Amgen, Ligand Pharmaceuticals, and MGI Pharma for clinical studies in immune thrombocytopenic purpura.
Keith R. McCrae, MD
Professor of Medicine
Case Western Reserve University School of Medicine
Cleveland
OH
利益声明
KRM declares that he has no competing interests.
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