光化性角化病

de Berker D, McGregor JM, Mohd Mustapa MF, et al. British Association of Dermatologists' guidelines for the care of patients with actinic keratosis 2017. Br J Dermatol. 2017 Jan;176(1):20-43. 摘要

Eisen DB, Asgari MM, Bennett DD, et al. Guidelines of care for the management of actinic keratosis. J Am Acad Dermatol. 2021 Oct;85(4):e209-33.全文  摘要

European Dermatology Forum. Evidence and consensus based (S3) guidelines for the treatment of actinic keratosis. 2015 [internet publication].全文

Eisen DB, Dellavalle RP, Frazer-Green L, et al. Focused update: guidelines of care for the management of actinic keratosis. J Am Acad Dermatol. 2022 Aug;87(2):373-4.e5.全文  摘要

1. Moy R. Clinical presentation of actinic keratosis and squamous cell carcinoma. J Am Acad Dermatol. 2000 Jan;42(1 Pt 2):8-10. 摘要

2. Berman B, Bienstock L, Kuritzky L, et al. Primary Care Education Consortium; Texas Academy of Family Physicians. Actinic keratoses: sequelae and treatments. Recommendations from a consensus panel. J Fam Pract. 2006 May;55(5):suppl 1-8. 摘要

3. Hawrot A, Alam M, Ratner D. Squamous cell carcinoma. Curr Probl Dermatol. 2003 May 1;15(3):91-133.

4. Schwartz RA. The actinic keratosis: a perspective and update. Dermatol Surg. 1997 Nov;23(11):1009-19. 摘要

5. Kuflik AS, Schwartz RA. Actinic keratosis and squamous cell carcinoma. Am Fam Physician. 1994 Mar;49(4):817-20. 摘要

6. Chung HJ, McGuigan KL, Osley KL, et al. Pigmented solar (actinic) keratosis: an underrecognized collision lesion. J Am Acad Dermatol. 2013 Apr;68(4):647-53. 摘要

7. Yu RC, Pryce DW, Macfarlane AW, et al. A histopathological study of 643 cutaneous horns. Br J Dermatol. 1991 May;124(5):449-52 摘要

8. Schosser RH, Hodge SJ, Gaba CR, et al. Cutaneous horns: a histopathologic study. South Med J. 1979 Sep;72(9):1129-31. 摘要

9. Hemminki K, Zhang H, Czene K. Time trends and familial risks in squamous cell carcinoma of the skin. Arch Dermatol. 2003 Jul;139(7):885-9.全文  摘要

10. Diepgen TL, Mahler V. The epidemiology of skin cancer. Br J Dermatol. 2002 Apr;146 Suppl 61:1-6. 摘要

11. Christenson LJ, Borrowman TA, Vachon CM, et al. Incidence of basal cell and squamous cell carcinomas in a population younger than 40 years. JAMA. 2005 Aug 10;294(6):681-90.全文  摘要

12. de Berker D, McGregor JM, Mohd Mustapa MF, et al. British Association of Dermatologists' guidelines for the care of patients with actinic keratosis 2017. Br J Dermatol. 2017 Jan;176(1):20-43. 摘要

13. Anwar J, Wrone DA, Kimyai-Asadi A, et al. The development of actinic keratosis into invasive squamous cell carcinoma: evidence and evolving classification schemes. Clin Dermatol. 2004 May-Jun;22(3):189-96. 摘要

14. Helfand M, Gorman AK, Mahon S, et al; US Department of Health and Human Services. Actinic keratoses: final report. May 2001 [internet publication].全文

15. Lookingbill DP, Lookingbill GL, Leppard B. Actinic damage and skin cancer in albinos in northern Tanzania: findings in 164 patients enrolled in an outreach skin care program. J Am Acad Dermatol. 1995 Apr;32(4):653-8. 摘要

16. Lehmann AR, Bridges BA. Sunlight-induced cancer: some new aspects and implications of the xeroderma pigmentosum model. Br J Dermatol. 1990 Apr;122 Suppl 35:115-9. 摘要

17. Lambert WC, Kuo HR, Lambert MW. Xeroderma pigmentosum. Dermatol Clin. 1995 Jan;13(1):169-209. 摘要

18. Luande J, Henschke CI, Mohammed N. The Tanzanian human albino skin. Natural history. Cancer. 1985 Apr 15;55(8):1823-8. 摘要

19. Memon AA, Tomenson JA, Bothwell J. Prevalence of solar damage and actinic keratosis in a Merseyside population. Br J Dermatol. 2000 Jun;142(6):1154-9. 摘要

20. Zagula-Mally ZW, Rosenberg EW, Kashgarian M. Frequency of skin cancer and solar keratoses in a rural southern county as determined by population sampling. Cancer. 1974 Aug;34(2):345-9. 摘要

21. Frost C, Williams G, Green A. High incidence and regression rates of solar keratoses in a Queensland community. J Invest Dermatol. 2000 Aug;115(2):273-7.全文  摘要

22. Green A, Beardmore G, Hart V, et al. Skin cancer in a Queensland population. J Am Acad Dermatol. 1988 Dec;19(6):1045-52. 摘要

23. Cooper KD, Fox P, Neises G, et al. Effects of ultraviolet radiation on human epidermal cell alloantigen presentation: initial depression of Langerhans cell-dependent function is followed by the appearance of T6- Dr+ cells that enhance epidermal alloantigen presentation. J Immunol. 1985 Jan;134(1):129-37. 摘要

24. Granstein RD, Askari M, Whitaker D, et al. Epidermal cells in activation of suppressor lymphocytes: further characterization. J Immunol. 1987 Jun 15;138(12):4055-62. 摘要

25. Winkelmann, Baldes EJ, Zollman PE. Squamous cell tumors induced in hairless mice with ultraviolet light. J Invest Dermatol. 1960 Feb;34:131-8. 摘要

26. Nomura T, Nakajima H, Hongyo T, et al. Induction of cancer, actinic keratosis, and specific p53 mutations by UVB light in human skin maintained in severe combined immunodeficient mice. Cancer Res. 1997 Jun 1;57(11):2081-4.全文  摘要

27. Levine AJ, Momand J, Finlay CA. The p53 tumour suppressor gene. Nature. 1991 Jun 6;351(6326):453-6. 摘要

28. Fu W, Cockerell CJ. The actinic (solar) keratosis: a 21st-century perspective. Arch Dermatol. 2003 Jan;139(1):66-70. 摘要

29. Del Rosso JQ. Current regimens and guideline implications for the treatment of actinic keratosis: proceedings of a clinical roundtable at the 2011 Winter Clinical Dermatology Conference. Cutis. 2011 Jul;88(1):suppl 1-8. 摘要

30. Vogelstein B, Kinzler KW. p53 function and dysfunction. Cell. 1992 Aug 21;70(4):523-6. 摘要

31. Lane DP. Cancer. p53, guardian of the genome. Nature. 1992 Jul 2;358(6381):15-6. 摘要

32. Satchell AC, Barnetson RS, Halliday GM. Increased Fas ligand expression by T cells and tumour cells in the progression of actinic keratosis to squamous cell carcinoma. Br J Dermatol. 2004 Jul;151(1):42-9. 摘要

33. Clifford JL, Walch E, Yang X, et al. Suppression of type I interferon signaling proteins is an early event in squamous skin carcinogenesis. Clin Cancer Res. 2002 Jul;8(7):2067-72.全文  摘要

34. Yaar M, Karassik RL, Schnipper LE, et al. Effects of alpha and beta interferons on cultured human keratinocytes. J Invest Dermatol. 1985 Jul;85(1):70-4. 摘要

35. Bromberg JF, Horvath CM, Wen Z, et al. Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7673-8.全文  摘要

36. Smit NP, Vink AA, Kolb RM, et al. Melanin offers protection against induction of cyclobutane pyrimidine dimers and 6-4 photoproducts by UVB in cultured human melanocytes. Photochem Photobiol. 2001 Sep;74(3):424-30. 摘要

37. Ortonne JP. Photoprotective properties of skin melanin. Br J Dermatol. 2002 Apr;146 Suppl 61:7-10. 摘要

38. Frost CA, Green AC. Epidemiology of solar keratoses. Br J Dermatol. 1994 Oct;131(4):455-64. 摘要

39. Giles GG, Marks R, Foley P. Incidence of non-melanocytic skin cancer treated in Australia. Br Med J (Clin Res Ed). 1988 Jan 2;296(6614):13-7.全文  摘要

40. Marks R, Jolley D, Lectsas S, Foley P. The role of childhood exposure to sunlight in the development of solar keratoses and non-melanocytic skin cancer. Med J Aust. 1990 Jan 15;152(2):62-6. 摘要

41. Salasche SJ. Epidemiology of actinic keratoses and squamous cell carcinoma. J Am Acad Dermatol. 2000 Jan;42(1 Pt 2):4-7. 摘要

42. Stockfleth E, Ulrich C, Meyer T, et al. Epithelial malignancies in organ transplant patients: clinical presentation and new methods of treatment. Recent Results Cancer Res. 2002;160:251-8. 摘要

43. Ulrich C, Schmook T, Sachse MM, et al. Comparative epidemiology and pathogenic factors for nonmelanoma skin cancer in organ transplant patients. Dermatol Surg. 2004 Apr;30(4 Pt 2):622-7. 摘要

44. Thompson SC, Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med. 1993 Oct 14;329(16):1147-51. 摘要

45. Naylor MF, Boyd A, Smith DW, et al. High sun protection factor sunscreens in the suppression of actinic neoplasia. Arch Dermatol. 1995 Feb;131(2):170-5. 摘要

46. Rigel DS. Photoprotection: a 21st century perspective. Br J Dermatol. 2002 Apr;146 Suppl 61:34-7. 摘要

47. Darlington S, Williams G, Neale R, et al. A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses. Arch Dermatol. 2003 Apr;139(4):451-5.全文  摘要

48. Eisen DB, Asgari MM, Bennett DD, et al. Guidelines of care for the management of actinic keratosis. J Am Acad Dermatol. 2021 Oct;85(4):e209-33.全文  摘要

49. Black HS, Herd JA, Goldberg LH, et al. Effect of a low-fat diet on the incidence of actinic keratosis. N Engl J Med. 1994 May 5;330(18):1272-5. 摘要

50. Zalaudek I, Giacomel J, Argenziano G, et al. Dermoscopy of facial nonpigmented actinic keratosis. Br J Dermatol. 2006 Nov;155(5):951-6. 摘要

51. Zalaudek I, Giacomel J, Schmid K, et al. Dermatoscopy of facial actinic keratosis, intraepidermal carcinoma, and invasive squamous cell carcinoma: A progression model. J Am Acad Dermatol. 2012 Apr;66(4):589-97. 摘要

52. Quaedvlieg PJ, Tirsi E, Thissen MR, et al. Actinic keratosis: how to differentiate the good from the bad ones? Eur J Dermatol. 2006 Jul-Aug;16(4):335-9. 摘要

53. Elder DE, Elenitsas R, Johnson Jr. BL, et al. Lever's histopathology of the skin. 9th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005.

54. Stolz W, Braun-Falco O, Bilek P, et al. Color atlas of dermatoscopy. 1st ed. London, UK: Blackwell Science Ltd; 1994.

55. Menzies SW, Crotty KA, Ingvar C, et al. An atlas of surface microscopy of pigmented skin lesions. 1st ed. Sydney, Australia: McGraw-Hill Book Company Australia Pty Limited; 1996.

56. Donnelly AM, Halbert AR, Rohr JB. Discoid lupus erythematosus. Australas J Dermatol. 1995 Feb;36(1):3-10; quiz 11-2. 摘要

57. Weber F, Fritsch P. Clinical differential diagnosis of cutaneous lupus erythematosus. In: Kuhn A, Lehmann P, Ruzica T, eds. Cutaneous lupus erythematosus. Berlin: Springer-Verlag; 2005.

58. Kontos AP, Jirsari M, Jacobsen G, et al. Immunoglobulin M predominance in cutaneous lupus erythematosus. J Cutan Pathol. 2005 May;32(5):352-5. 摘要

59. Zedek DC, Smith ET Jr, Hitchcock MG, et al. Cutaneous lupus erythematosus simulating squamous neoplasia: the clinicopathologic conundrum and histopathologic pitfalls. J Am Acad Dermatol. 2007 Jun;56(6):1013-20. 摘要

60. Perniciaro C, Randle HW, Perry HO. Hypertrophic discoid lupus erythematosus resembling squamous cell carcinoma. Dermatol Surg. 1995 Mar;21(3):255-7. 摘要

61. Uitto J, Santa-Cruz DJ, Eisen AZ, et al. Verrucous lesion in patients with discoid lupus erythematosus. Clinical, histopathological and immunofluorescence studies. Br J Dermatol. 1978 May;98(5):507-20. 摘要

62. Patel P, Werth V. Cutaneous lupus erythematosus: a review. Dermatol Clin. 2002 Jul;20(3):373-85. 摘要

63. Reid C. Drug treatment of cutaneous lupus. Am J Clin Dermatol. 2000 Nov-Dec;1(6):375-9. 摘要

64. Tebbe B, Orfanos CE. Epidemiology and socioeconomic impact of skin disease in lupus erythematosus. Lupus. 1997 Feb 1;6(2):96-104. 摘要

65. Sontheimer RD. Subacute cutaneous lupus erythematosus: a decade's perspective. Med Clin North Am. 1989 Sep;73(5):1073-90. 摘要

66. Telfer NR, Chalmers RJ, Whale K, et al. The role of streptococcal infection in the initiation of guttate psoriasis. Arch Dermatol. 1992 Jan;128(1):39-42. 摘要

67. Christophers E, Kiene P. Guttate and plaque psoriasis. Dermatol Clin. 1995 Oct;13(4):751-6. 摘要

68. Mehregan DR, Hamzavi F, Brown K. Large cell acanthoma. Int J Dermatol. 2003 Jan;42(1):36-9. 摘要

69. Roewert HJ, Ackerman AB. Large-cell acanthoma is a solar lentigo. Am J Dermatopathol. 1992 Apr;14(2):122-32. 摘要

70. Sanchez Yus E, del Rio E, Requena L. Large-cell acanthoma is a distinctive condition. Am J Dermatopathol. 1992 Apr;14(2):140-7. 摘要

71. Rahbari H, Pinkus H. Large cell acanthoma. One of the actinic keratoses. Arch Dermatol. 1978 Jan;114(1):49-52. 摘要

72. Sanchez Yus E, de Diego V, Urrutia S. Large cell acanthoma. A cytologic variant of Bowen's disease? Am J Dermatopathol. 1988 Jun;10(3):197-208. 摘要

73. Uhlenhake EE, Sangueza OP, Lee AD, et al. Spreading pigmented actinic keratosis: a review. J Am Acad Dermatol. 2010 Sep;63(3):499-506. 摘要

74. Yantsos VA, Conrad N, Zabawski E, et al. Incipient intraepidermal cutaneous squamous cell carcinoma: a proposal for reclassifying and grading solar (actinic) keratoses. Semin Cutan Med Surg. 1999 Mar;18(1):3-14. 摘要

75. Carag HR, Prieto VG, Yballe LS, et al. Utility of step sections: demonstration of additional pathological findings in biopsy samples initially diagnosed as actinic keratosis. Arch Dermatol. 2000 Apr;136(4):471-5.全文  摘要

76. Scurry J. Grading of actinic keratoses. J Am Acad Dermatol. 2001 Jun;44(6):1052-3. 摘要

77. European Dermatology Forum. Evidence and consensus based (S3) guidelines for the treatment of actinic keratosis. 2015 [internet publication].全文

78. Chiarello SE. Cryopeeling (extensive cryosurgery) for treatment of actinic keratoses: an update and comparison. Dermatol Surg. 2000 Aug;26(8):728-32 摘要

79. Gupta AK, Paquet M, Villanueva E, et al. Interventions for actinic keratoses. Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD004415.全文  摘要

80. Patel G, Armstrong AW, Eisen DB. Efficacy of photodynamic therapy vs other interventions in randomized clinical trials for the treatment of actinic keratoses: a systematic review and meta-analysis. JAMA Dermatol. 2014 Dec;150(12):1281-8.全文  摘要

81. Brian Jiang SI, Kempers S, Rich P, et al. A randomized, vehicle-controlled phase 3 study of aminolevulinic acid photodynamic therapy for the treatment of actinic keratoses on the upper extremities. Dermatol Surg. 2019 Jul;45(7):890-7. 摘要

82. Touma D, Yaar M, Whitehead S, et al. A trial of short incubation, broad-area photodynamic therapy for facial actinic keratoses and diffuse photodamage. Arch Dermatol. 2004 Jan;140(1):33-40.全文  摘要

83. Braathen LR, Szeimies RM, Basset-Seguin N, et al; International Society for Photodynamic Therapy in Dermatology. Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005. J Am Acad Dermatol. 2007 Jan;56(1):125-43. 摘要

84. Piacquadio DJ, Chen DM, Farber HF, et al. Photodynamic therapy with aminolevulinic acid topical solution and visible blue light in the treatment of multiple actinic keratoses of the face and scalp: investigator-blinded, phase 3, multicenter trials. Arch Dermatol. 2004 Jan;140(1):41-6.全文  摘要

85. Fayter D, Corbett M, Heirs M, et al. A systematic review of photodynamic therapy in the treatment of pre-cancerous skin conditions, Barrett's oesophagus and cancers of the biliary tract, brain, head and neck, lung, oesophagus and skin. Health Technol Assess. 2010 Jul;14(37):1-288. 摘要

86. Morton CA, Szeimies RM, Basset-Seguin N, et al. European Dermatology Forum guidelines on topical photodynamic therapy 2019 part 1: treatment delivery and established indications - actinic keratoses, Bowen's disease and basal cell carcinomas. J Eur Acad Dermatol Venereol. 2019 Dec;33(12):2225-38.全文  摘要

87. Jiang AJ, Soon SL, Rullan P, et al. Chemical peels as field therapy for actinic keratoses: a systematic review. Dermatol Surg. 2021 Oct 1;47(10):1343-6. 摘要

88. Holzer G, Pinkowicz A, Radakovic S, et al. Randomized controlled trial comparing 35% trichloroacetic acid peel and 5-aminolaevulinic acid photodynamic therapy for treating multiple actinic keratosis. Br J Dermatol. 2017 May;176(5):1155-61. 摘要

89. Jansen MHE, Kessels JPHM, Nelemans PJ, et al. Randomized trial of four treatment approaches for actinic keratosis. N Engl J Med. 2019 Mar 7;380(10):935-46.全文  摘要

90. Krawtchenko N, Roewert-Huber J, Ulrich M, et al. A randomised study of topical 5% imiquimod vs. topical 5-fluorouracil vs. cryosurgery in immunocompetent patients with actinic keratoses: a comparison of clinical and histological outcomes including 1-year follow-up. Br J Dermatol. 2007 Dec;157 (Suppl 2):34-40. 摘要

91. Stockfleth E, Zwingers T, Willers C. Recurrence rates and patient assessed outcomes of 0.5% 5-fluorouracil in combination with salicylic acid treating actinic keratoses. Eur J Dermatol. 2012 May-Jun;22(3):370-4. 摘要

92. Kaur RR, Alikhan A, Maibach HI. Comparison of topical 5-fluorouracil formulations in actinic keratosis treatment. J Dermatolog Treat. 2010 Sep;21(5):267-71. 摘要

93. Loven K, Stein L, Furst K, et al. Evaluation of the efficacy and tolerability of 0.5% fluorouracil cream and 5% fluorouracil cream applied to each side of the face in patients with actinic keratosis. Clin Ther. 2002 Jun;24(6):990-1000. 摘要

94. Swanson N, Abramovits W, Berman B, et al. Imiquimod 2.5% and 3.75% for the treatment of actinic keratoses: results of two placebo-controlled studies of daily application to the face and balding scalp for two 2-week cycles. J Am Acad Dermatol. 2010 Apr;62(4):582-90. 摘要

95. Hanke CW, Beer KR, Stockfleth E, et al. Imiquimod 2.5% and 3.75% for the treatment of actinic keratoses: results of two placebo-controlled studies of daily application to the face and balding scalp for two 3-week cycles. J Am Acad Dermatol. 2010 Apr;62(4):573-81. 摘要

96. Stockfleth E, Christophers E, Benninghoff B, et al. Low incidence of new actinic keratoses after topical 5% imiquimod cream treatment: a long-term follow-up study. Arch Dermatol. 2004 Dec;140(12):1542. 摘要

97. Lee PK, Harwell WB, Loven KH, et al. Long-term clinical outcomes following treatment of actinic keratosis with imiquimod 5% cream. Dermatol Surg. 2005 Jun;31(6):659-64. 摘要

98. Gebauer K, Brown P, Varigos G. Topical diclofenac in hyaluronan gel for the treatment of solar keratoses. Australas J Dermatol. 2003 Feb;44(1):40-3. 摘要

99. Wolf JE Jr, Taylor JR, Tschen E, et al. Topical 3.0% diclofenac in 2.5% hyaluronan gel in the treatment of actinic keratoses. Int J Dermatol. 2001 Nov;40(11):709-13. 摘要

100. Nelson C, Rigel D. Long-term follow up of diclofenac sodium 3% in 2.5% hyaluronic acid gel for actinic keratosis: one-year evaluation. J Clin Aesth Dermatol. 2009 Jul;2(7):20-5.全文

101. Berman B, Villa AM, Ramirez CC. Mechanisms of action of new treatment modalities for actinic keratosis. J Drugs Dermatol. 2006 Feb;5(2):167-73. 摘要

102. Smith SR, Morhenn VB, Piacquadio DJ. Bilateral comparison of the efficacy and tolerability of 3% diclofenac sodium gel and 5% 5-fluorouracil cream in the treatment of actinic keratoses of the face and scalp. J Drugs Dermatol. 2006 Feb;5(2):156-9. 摘要

103. Iraji F, Siadat AH, Asilian A, et al. The safety of diclofenac for the management and treatment of actinic keratoses. Expert Opin Drug Saf. 2008 Mar;7(2):167-72. 摘要

104. ClinicalTrials.gov. A multi-center study to evaluate the efficacy and safety of KX2-391 ointment 1% on AK on face or scalp (AK003). April 2021 [internet publication].全文

105. ClinicalTrials.gov. A multi-center study to evaluate the efficacy and safety of KX2-391 ointment 1% on actinic keratosis on face or scalp (AK004). March 2021 [internet publication].全文

106. Eisen DB, Dellavalle RP, Frazer-Green L, et al. Focused update: guidelines of care for the management of actinic keratosis. J Am Acad Dermatol. 2022 Aug;87(2):373-4.e5.全文  摘要

107. Coleman WP 3rd, Yarborough JM, Mandy SH. Dermabrasion for prophylaxis and treatment of actinic keratoses. Dermatol Surg. 1996 Jan;22(1):17-21. 摘要

108. Perkins SW, Sklarew EC. Prevention of facial herpetic infections after chemical peel and dermabrasion: new treatment strategies in the prophylaxis of patients undergoing procedures of the perioral area. Plast Reconstr Surg. 1996 Sep;98(3):427-35. 摘要

109. Harmon CB. Dermabrasion. Dermatol Clin. 2001 Jul;19(3):439-42, viii. 摘要

110. Fewkes JL, Cheney ML, Pollack SV. Dermabrasion. In: Illustrated atlas of cutaneous surgery. 1st ed. Philadelphia, PA: J.B. Lippincott Company; 1992:26.1-26.11.

111. Orenstein A, Goldan O, Weissman O, et al. A new modality in the treatment of actinic cheilitis using the Er:YAG laser. J Cosmet Laser Ther. 2007 Mar;9(1):23-5. 摘要

112. Chen AC, Martin AJ, Choy B, et al. A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention. N Engl J Med. 2015 Oct 22;373(17):1618-26.全文  摘要

113. Dohil MA. Efficacy, Safety, and Tolerability of 4% 5-Fluorouracil Cream in a Novel Patented Aqueous Cream Containing Peanut Oil Once Daily Compared With 5% 5-Fluorouracil Cream Twice Daily: Meeting the Challenge in the Treatment of Actinic Keratosis. J Drugs Dermatol. 2016 Oct 1;15(10):1218-24. 摘要

114. Marks R, Rennie G, Selwood TS. Malignant transformation of solar keratoses to squamous cell carcinoma. Lancet. 1988 Apr 9;1(8589):795-7. 摘要

115. Glogau RG. The risk of progression to invasive disease. J Am Acad Dermatol. 2000 Jan;42(1 Pt 2):23-4. 摘要

116. Marks R, Foley P, Goodman G, et al. Spontaneous remission of solar keratoses: the case for conservative management. Br J Dermatol. 1986 Dec;115(6):649-55. 摘要

117. Suchniak JM, Baer S, Goldberg LH. High rate of malignant transformation in hyperkeratotic actinic keratoses. J Am Acad Dermatol. 1997 Sep;37(3 Pt 1):392-4. 摘要

118. Ehrig T, Cockerell C, Piacquadio D, et al. Actinic keratoses and the incidence of occult squamous cell carcinoma: a clinical-histopathologic correlation. Dermatol Surg. 2006 Oct;32(10):1261-5. 摘要

119. Kinlen LJ, Sheil AG, Peto J, et al. Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs. Br Med J. 1979 Dec 8;2(6203):1461-6.全文  摘要

120. Blohme I, Larko O. Skin lesions in renal transplant patients after 10-23 years of immunosuppressive therapy. Acta Derm Venereol. 1990;70(6):491-4. 摘要

121. Walder BK, Robertson MR, Jeremy D. Skin cancer and immunosuppression. Lancet. 1971 Dec 11;2(7737):1282-3. 摘要

122. Hardie IR, Strong RW, Hartley LC, et al. Skin cancer in Caucasian renal allograft recipients living in a subtropical climate. Surgery. 1980 Feb;87(2):177-83. 摘要

123. Bouwes Bavinck JN, Hardie DR, et al. The risk of skin cancer in renal transplant recipients in Queensland, Australia. A follow-up study. Transplantation. 1996 Mar 15;61(5):715-21. 摘要

124. Dinehart SM. The treatment of actinic keratoses. J Am Acad Dermatol. 2000 Jan;42(1 Pt 2):25-8. 摘要

125. Lubritz RR, Smolewski SA. Cryosurgery cure rate of actinic keratoses. J Am Acad Dermatol. 1982 Nov;7(5):631-2. 摘要

126. Thai KE, Fergin P, Freeman M, et al A prospective study of the use of cryosurgery for the treatment of actinic keratoses. Int J Dermatol. 2004 Sep;43(9):687-92. 摘要

127. Zouboulis CC, Rohrs H. Cryosurgical treatment of actinic keratoses and evidence-based review. Hautarzt. 2005 Apr;56(4):353-8. 摘要

128. Stockfleth E, Kerl H; Guideline Subcommittee of the European Dermatology Forum. Guidelines for the management of actinic keratoses. Eur J Dermatol. 2006 Nov-Dec;16(6):599-606. 摘要

129. Cox NH, Eedy DJ, Morton CA; Therapy Guidelines and Audit Subcommittee, British Association of Dermatologists. Guidelines for management of Bowen's disease: 2006 update. Br J Dermatol. 2007 Jan;156(1):11-21. 摘要

130. Montgomery H, Dorffel J. Verruca senilis und keratoma senile. Arch f Dermat u Syphil (Berlin). 1932;166:286-97.

131. Rowe DE, Carroll RJ, Day CL Jr. Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection. J Am Acad Dermatol. 1992 Jun;26(6):976-90. 摘要

132. Czarnecki D, Staples M, Mar A, et al. Metastases from squamous cell carcinoma of the skin in southern Australia. Dermatology. 1994;189(1):52-4. 摘要

133. Lang K, Schulte KW, Ruzicka T, et al. Aminolevulinic acid (Levulan) in photodynamic therapy of actinic keratoses. Skin Therapy Lett. 2001 Sep;6(10):1-2, 5. 摘要

134. North P, Zembowicz A, Mihm M, et al. Sun induced skin diseases. Pathol Int. 2004;54:S559-69.

135. Monheit GD. Medium-depth chemical peels. Dermatol Clin. 2001 Jul;19(3):413-25, vii. 摘要

136. Grimes PE. The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups. Dermatol Surg. 1999 Jan;25(1):18-22. 摘要

137. Kligman D, Kligman AM. Salicylic acid peels for the treatment of photoaging. Dermatol Surg. 1998 Mar;24(3):325-8. 摘要

138. Ghersetich I, Teofoll P, Gantcheva M, et al. Chemical peeling: how, when, why? J Eur Acad Dermatol Venereol. 1997 Jan;8(1):1-11.

139. Rubin MG. Salicylic acid peels (nonfacial). In: Rubin MG, ed. Manual of chemical peels. Superficial and medium depth. 1st ed. Philadelphia, PA: J.B. Lippincott Company; 1995:103-9.

140. Dolezal J. Jessner's peels. In: Rubin MG, ed. Manual of chemical peels. Superficial and medium depth. 1st ed. Philadelphia, PA: J.B. Lippincott Company; 1995:79-88.