最近审阅: 1 十一月 2020
最近更新: 06 四月 2018

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • Gottron 丘疹
  • 向阳性皮疹,伴有或不伴有眶周水肿
  • 紫红色斑片
  • 甲周红斑,甲襞毛细血管扩张,角化过度
  • “机械师手”
  • 近端肌肉无力

其他诊断因素

  • 光敏感性
  • 血管萎缩性皮肤异色症
  • 瘙痒
  • 乏力和不适感
  • 呼吸困难
  • 体重减轻
  • 发热
  • 肌痛
  • 关节痛
  • 吞咽困难
  • 心悸和晕厥
  • 雷诺现象
  • 皮肤钙质沉着
  • 红皮病
  • 水疱大疱性损害
  • 白细胞破碎性血管炎
  • 皮肤坏死
  • 非疤痕性秃发

危险因素

  • 遗传易感性
  • 双峰年龄分布:儿童和年龄 >40 岁的成人
  • 女性
  • 黑人
  • 紫外线辐射
  • 感染性病原体
  • 药物
  • 免疫

诊断性检查

首要检查

  • 血清肌酸激酶 (CK)
  • 血清醛缩酶
  • 肌肉活检
  • 肌电图(EMG)
  • 皮肤活检
  • 抗核抗体 (ANA)
更多 首要检查

需考虑的检查

  • 肌炎特异性抗体
  • 肌肉 MRI
  • 心电图 (ECG)
  • 超声心动图
  • 心脏肌钙蛋白I
  • 胸部 X 线检查 (CXR)
  • 肺功能检查 (PFT)
  • 高分辨率胸部 CT 扫描
  • 钡餐或吞钡透视
更多 需考虑的检查

治疗流程

撰稿人

Consultant Physician and Rheumatologist

Department of Rheumatology

Centre for Rheumatic Diseases

Glasgow Royal Infirmary

Glasgow

UK

利益声明

SAS declares that she has no competing interests.

Consultant Physician and Rheumatologist

Department of Rheumatology

Glasgow Royal Infirmary

Glasgow

UK

利益声明

RM holds shares in GSK to the value less than £12,000.

Dr Sarah A. Saunders and Dr Rajan Madhok would like to gratefully acknowledge Dr Nicola Alcorn, a previous contributor to this monograph. NA declares she has no competing interests.

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Assistant Professor of Neurology

Director of EMG Laboratory & Peripheral Neuropathy Center

Department of Neurology & Neurosciences

New Jersey Medical School

Newark

NJ

利益声明

NS declares that he has no competing interests.

Physician

Department of Neurology

Penn Presbyterian Medical Center

University of Pennsylvania Health System

Philadelphia

PA

利益声明

SK declares that he has no competing interests.

Assistant Professor

Associate Director

Arthritis Program

Director

Behcet's Syndrome Center

Seligman Center for Advanced Therapeutics

New York University Hospital for Joint Diseases

New York

NY

利益声明

YY has served as a consultant for Bristol-Myers Squibb, Roche, Celgene, Centocor, and UCB, and has been a speaker for Pfizer and Bristol-Myers Squibb.

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